Deconstructing Complex Multimorbidity in the Very Old: Findings from the Newcastle 85+ Study
Joint Authors
Collerton, Joanna
Jagger, Carol
Yadegarfar, Mohammad E.
Davies, Karen
Parker, Stuart G.
Robinson, Louise
Kirkwood, Thomas B. L.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-13
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Objectives.
To examine the extent and complexity of the morbidity burden in 85-year-olds; identify patterns within multimorbidity; and explore associations with medication and healthcare use.
Participants.
710 men and women; mean (SD) age 85.5 (0.4) years.
Methods.
Data on 20 chronic conditions (diseases and geriatric conditions) ascertained from general practice records and participant assessment.
Cluster analysis within the multimorbid sample identified subgroups sharing morbidity profiles.
Clusters were compared on medication and healthcare use.
Results.
92.7% (658/710) of participants had multimorbidity; median number of conditions: 4 (IQR 3–6).
Cluster analysis (multimorbid sample) identified five subgroups sharing similar morbidity profiles; 60.0% (395/658) of participants belonged to one of two high morbidity clusters, with only 4.9% (32/658) in the healthiest cluster.
Healthcare use was high, with polypharmacy (≥5 medications) in 69.8% (459/658).
Between-cluster differences were found in medication count ( p = 0.0001 ); hospital admissions ( p = 0.022 ); and general practitioner ( p = 0.034 ) and practice nurse consultations ( p = 0.011 ).
Morbidity load was related to medication burden and use of some, but not all, healthcare services.
Conclusions.
The majority of 85-year-olds had extensive and complex morbidity.
Elaborating participant clusters sharing similar morbidity profiles will help inform future healthcare provision and the identification of common underlying biological mechanisms.
American Psychological Association (APA)
Collerton, Joanna& Jagger, Carol& Yadegarfar, Mohammad E.& Davies, Karen& Parker, Stuart G.& Robinson, Louise…[et al.]. 2016. Deconstructing Complex Multimorbidity in the Very Old: Findings from the Newcastle 85+ Study. BioMed Research International،Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1099132
Modern Language Association (MLA)
Collerton, Joanna…[et al.]. Deconstructing Complex Multimorbidity in the Very Old: Findings from the Newcastle 85+ Study. BioMed Research International No. 2016 (2016), pp.1-15.
https://search.emarefa.net/detail/BIM-1099132
American Medical Association (AMA)
Collerton, Joanna& Jagger, Carol& Yadegarfar, Mohammad E.& Davies, Karen& Parker, Stuart G.& Robinson, Louise…[et al.]. Deconstructing Complex Multimorbidity in the Very Old: Findings from the Newcastle 85+ Study. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1099132
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099132