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Silver-Coated Hip Megaprosthesis in Oncological Limb Savage Surgery
Joint Authors
Donati, F.
Di Giacomo, G.
D’Adamio, S.
Ziranu, A.
Careri, S.
Rosa, MA.
Maccauro, Giulio
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Silver coating has demonstrated good antimicrobial activity and low toxicity.
Silver-coated megaprostheses have been introduced in oncological musculoskeletal surgery considering the high rate of infection.
We conducted a retrospective analysis on 68 cases of primary or metastatic bone tumors, affecting the proximal femur, treated between 2005 and 2016 with wide margins resection and tumor implants reconstruction.
All patients were treated by the same surgeon, with antibiotic prophylaxis according to a standard protocol.
In 55.9% of patients silver-coated hip hemiarthroplasty was implanted; in the remaining 44.1% uncoated megaprostheses were implanted.
Patients were reevaluated recording the complications and focusing the analysis on infective complications.
The average follow-up was 46.5 months.
No patient has shown any sign of local or general silver toxicity.
A SEM analysis was conducted on the 3-silver-coated hip hemiarthroplasty explanted confirming a severe degradation with a small amount of residual silver on the coating surface.
Silver-coated hip prostheses have a lower rate of early infection than traditional implants but showed a reduction of antimicrobial activity for silver coating wear.
We recommend using silver-coated prosthesis as primary implants for limb salvage surgery, in primary or metastatic bone tumors affecting the proximal femur, considering the absence of signs of toxicity and the lower rate of early infection.
American Psychological Association (APA)
Donati, F.& Di Giacomo, G.& D’Adamio, S.& Ziranu, A.& Careri, S.& Rosa, MA.…[et al.]. 2016. Silver-Coated Hip Megaprosthesis in Oncological Limb Savage Surgery. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1099229
Modern Language Association (MLA)
Donati, F.…[et al.]. Silver-Coated Hip Megaprosthesis in Oncological Limb Savage Surgery. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1099229
American Medical Association (AMA)
Donati, F.& Di Giacomo, G.& D’Adamio, S.& Ziranu, A.& Careri, S.& Rosa, MA.…[et al.]. Silver-Coated Hip Megaprosthesis in Oncological Limb Savage Surgery. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1099229
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099229