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How Effective and Safe Is Bronchial Thermoplasty in “Real Life” Asthmatics Compared to Those Enrolled in Randomized Clinical Trials?
Joint Authors
Arrigo, Rita
Failla, Giuseppe
Scichilone, Nicola
La Sala, Alba
Galeone, Carla
Benfante, Alida
Facciolongo, Nicola
Battaglia, Salvatore
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-08
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
There is limited information on the efficacy and safety of bronchial thermoplasty (BT) in real life.
We evaluated the outcomes of the randomized clinical trials for BT in severe asthmatics, in whom the exclusion criteria were not strictly controlled.
A case series of seven asthmatics (M/F: 4/3; age: 54.6 ± 2.9 years) is reported.
Subjects had a statistically significant improvement in AQLQ (from a mean of 3.96 ± 1.1 to 4.5 ± 1.2 and 5.5 ± 0.6 after 6 and 12 months of treatment; p = 0.0007 ) and in the ACQ score (from 2.77 ± 0.8 to 1.83 ± 1.2 and 1.5 ± 0.8 after 6 and 12 months; p < 0.001 ).
In the year after BT, severe exacerbations, salbutamol use, and OCS use were significantly lower compared with the 1-yr pretreatment period ( p < 0.001 ).
No ED visits and hospitalization occurred in the year after BT.
No changes in functional parameters were recorded.
Our investigation confirms the safety and efficacy of BT in severe asthmatics in real life settings.
American Psychological Association (APA)
Arrigo, Rita& Failla, Giuseppe& Scichilone, Nicola& La Sala, Alba& Galeone, Carla& Battaglia, Salvatore…[et al.]. 2016. How Effective and Safe Is Bronchial Thermoplasty in “Real Life” Asthmatics Compared to Those Enrolled in Randomized Clinical Trials?. BioMed Research International،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1099239
Modern Language Association (MLA)
Arrigo, Rita…[et al.]. How Effective and Safe Is Bronchial Thermoplasty in “Real Life” Asthmatics Compared to Those Enrolled in Randomized Clinical Trials?. BioMed Research International No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1099239
American Medical Association (AMA)
Arrigo, Rita& Failla, Giuseppe& Scichilone, Nicola& La Sala, Alba& Galeone, Carla& Battaglia, Salvatore…[et al.]. How Effective and Safe Is Bronchial Thermoplasty in “Real Life” Asthmatics Compared to Those Enrolled in Randomized Clinical Trials?. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1099239
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099239