Leukocyte-Reduced Platelet-Rich Plasma Treatment of Basal Thumb Arthritis: A Pilot Study
Joint Authors
Angele, Peter
Lang, Siegmund
Dendl, Lena-Marie
Huber, Michaela
Nerlich, Michael
Gehmert, Sanga
Loibl, Markus
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A positive effect of intra-articular platelet-rich plasma (PRP) injection has been discussed for osteoarthritic joint conditions in the last years.
The purpose of this study was to evaluate PRP injection into the trapeziometacarpal (TMC) joint.
We report about ten patients with TMC joint osteoarthritis (OA) that were treated with 2 intra-articular PRP injections 4 weeks apart.
PRP was produced using the Double Syringe System (Arthrex Inc., Naples, Florida, USA).
A total volume of 1.47 ± 0.25 mL PRP was injected at the first injection and 1.5 ± 0.41 mL at the second injection, depending on the volume capacity of the joint.
Patients were evaluated using VAS, strength measures, and the Mayo Wrist score and DASH score after 3 and 6 months.
VAS significantly decreased from 6.2 ± 1.6 to 5.4 ± 2.2 at six-month follow-up ( P < 0 .
05 ).
The DASH score was unaffected; however, the Mayo Wrist score significantly improved from 46.5 ± 18.6 to 67.5 ± 19.0 at six-month follow-up ( P = 0 .
05 ).
Grip was unaffected, whereas pinch declined from 6.02 ± 2.99 to 3.96 ± 1.77 at six-month follow-up ( P < 0 .
05 ).
We did not observe adverse events after the injection of PRP, except one occurrence of a palmar wrist ganglion, which resolved without treatment.
PRP injection for symptomatic TMC OA is a reasonable therapeutic option in early stages TMC OA and can be performed with little to no morbidity.
American Psychological Association (APA)
Loibl, Markus& Lang, Siegmund& Dendl, Lena-Marie& Nerlich, Michael& Angele, Peter& Gehmert, Sanga…[et al.]. 2016. Leukocyte-Reduced Platelet-Rich Plasma Treatment of Basal Thumb Arthritis: A Pilot Study. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1099266
Modern Language Association (MLA)
Loibl, Markus…[et al.]. Leukocyte-Reduced Platelet-Rich Plasma Treatment of Basal Thumb Arthritis: A Pilot Study. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1099266
American Medical Association (AMA)
Loibl, Markus& Lang, Siegmund& Dendl, Lena-Marie& Nerlich, Michael& Angele, Peter& Gehmert, Sanga…[et al.]. Leukocyte-Reduced Platelet-Rich Plasma Treatment of Basal Thumb Arthritis: A Pilot Study. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1099266
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099266