Effects of the Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Sexual Behavior in Normal Male Rats
Joint Authors
Tan, Paul V.
Ernestine, Nkwengoua
Nchegang, B.
Longo, F.
André Perfusion, Amang
Mezui, C.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-20
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
We studied prosexual effects of Eremomastax speciosa aqueous extract in male adult rats.
Materials and Methods.
100 and 500 mg/kg of extract were administered orally (days 0, 1, 4, 7, 14, and 28 (posttreatment)).
The sexual behavior of rats receiving a single dose (500 mg/kg) was also evaluated after pretreatment with Lω-NAME (10 mg/kg), haloperidol (1 mg/kg), or atropine (5 mg/kg).
Controls received distilled water or testosterone enanthate (20 mg/kg/day/3 days (s.c.) before the test).
Results.
The extract (days 1–14) had no significant effect on mount, intromission, and ejaculation frequencies but on day 28 (14 days after treatment), it increased frequency of mounts and intromissions at 500 mg/kg.
Mount, intromission, and ejaculation latencies reduced and postejaculatory intervals decreased but the effect did not persist 2 weeks after treatment.
Extract prosex effects were greatly reduced by atropine and completely abolished by haloperidol, while Lω-NAME increased mount latency and potentiated extract effect on intromission and ejaculation latencies.
Conclusion.
In summary, E.
speciosa extract can have positive effects on male sexual motivation and performance when administered for two weeks at the dose of 500 mg/kg.
The effects (dopaminergic and/or cholinergic dependent) tend to appear during the posttreatment period.
American Psychological Association (APA)
Nchegang, B.& Mezui, C.& Longo, F.& Ernestine, Nkwengoua& André Perfusion, Amang& Tan, Paul V.. 2016. Effects of the Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Sexual Behavior in Normal Male Rats. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1099352
Modern Language Association (MLA)
Nchegang, B.…[et al.]. Effects of the Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Sexual Behavior in Normal Male Rats. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1099352
American Medical Association (AMA)
Nchegang, B.& Mezui, C.& Longo, F.& Ernestine, Nkwengoua& André Perfusion, Amang& Tan, Paul V.. Effects of the Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Sexual Behavior in Normal Male Rats. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1099352
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099352