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Sézary Syndrome and Atopic Dermatitis: Comparison of Immunological Aspects and Targets
Joint Authors
Guenova, Emmanuella
Saulite, Ieva
Hoetzenecker, Wolfram
Weidinger, Stephan
Wehkamp, Ulrike
Cozzio, A.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-17
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Sézary syndrome (SS), an aggressive form of erythrodermic pruritic cutaneous T cell lymphoma (CTCL), from an immunological perspective characterized by increased Th2 cytokine levels, elevated serum IgE and impaired cellular immunity.
Not only the clinical appearance but also the hallmark immunological characteristics of SS often share striking similarities with acute flares of atopic dermatitis (AD), a common benign chronic inflammatory skin disease.
Given the overlap of several immunological features, the application of similar or even identical therapeutic approaches in certain stages of both diseases may come into consideration.
The aim of this review is to compare currently accepted immunological aspects and possible therapeutic targets in AD and SS.
American Psychological Association (APA)
Saulite, Ieva& Hoetzenecker, Wolfram& Weidinger, Stephan& Cozzio, A.& Guenova, Emmanuella& Wehkamp, Ulrike. 2016. Sézary Syndrome and Atopic Dermatitis: Comparison of Immunological Aspects and Targets. BioMed Research International،Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1099355
Modern Language Association (MLA)
Saulite, Ieva…[et al.]. Sézary Syndrome and Atopic Dermatitis: Comparison of Immunological Aspects and Targets. BioMed Research International No. 2016 (2016), pp.1-15.
https://search.emarefa.net/detail/BIM-1099355
American Medical Association (AMA)
Saulite, Ieva& Hoetzenecker, Wolfram& Weidinger, Stephan& Cozzio, A.& Guenova, Emmanuella& Wehkamp, Ulrike. Sézary Syndrome and Atopic Dermatitis: Comparison of Immunological Aspects and Targets. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1099355
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099355