Pediatric Traumatic Brain Injury and Autism: Elucidating Shared Mechanisms
Joint Authors
Singh, Rahul
Nguyen, Linda
Motwani, Kartik
Swatek, Michelle
Lucke-Wold, Brandon P.
Turner, Ryan C.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-15
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Pediatric traumatic brain injury (TBI) and autism spectrum disorder (ASD) are two serious conditions that affect youth.
Recent data, both preclinical and clinical, show that pediatric TBI and ASD share not only similar symptoms but also some of the same biologic mechanisms that cause these symptoms.
Prominent symptoms for both disorders include gastrointestinal problems, learning difficulties, seizures, and sensory processing disruption.
In this review, we highlight some of these shared mechanisms in order to discuss potential treatment options that might be applied for each condition.
We discuss potential therapeutic and pharmacologic options as well as potential novel drug targets.
Furthermore, we highlight advances in understanding of brain circuitry that is being propelled by improved imaging modalities.
Going forward, advanced imaging will help in diagnosis and treatment planning strategies for pediatric patients.
Lessons from each field can be applied to design better and more rigorous trials that can be used to improve guidelines for pediatric patients suffering from TBI or ASD.
American Psychological Association (APA)
Singh, Rahul& Turner, Ryan C.& Nguyen, Linda& Motwani, Kartik& Swatek, Michelle& Lucke-Wold, Brandon P.. 2016. Pediatric Traumatic Brain Injury and Autism: Elucidating Shared Mechanisms. Behavioural Neurology،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1099459
Modern Language Association (MLA)
Singh, Rahul…[et al.]. Pediatric Traumatic Brain Injury and Autism: Elucidating Shared Mechanisms. Behavioural Neurology No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1099459
American Medical Association (AMA)
Singh, Rahul& Turner, Ryan C.& Nguyen, Linda& Motwani, Kartik& Swatek, Michelle& Lucke-Wold, Brandon P.. Pediatric Traumatic Brain Injury and Autism: Elucidating Shared Mechanisms. Behavioural Neurology. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1099459
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099459