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Spike Code Flow in Cultured Neuronal Networks
Joint Authors
Hosokawa, Chie
Chen, Yen-Wei
Sawai, Hajime
Kamimura, Takuya
Yagi, Yasushi
Tamura, Shinichi
Nishitani, Yoshi
Miyoshi, Tomomitsu
Mizuno-Matsumoto, Yuko
Source
Computational Intelligence and Neuroscience
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-27
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
We observed spike trains produced by one-shot electrical stimulation with 8 × 8 multielectrodes in cultured neuronal networks.
Each electrode accepted spikes from several neurons.
We extracted the short codes from spike trains and obtained a code spectrum with a nominal time accuracy of 1%.
We then constructed code flow maps as movies of the electrode array to observe the code flow of “1101” and “1011,” which are typical pseudorandom sequence such as that we often encountered in a literature and our experiments.
They seemed to flow from one electrode to the neighboring one and maintained their shape to some extent.
To quantify the flow, we calculated the “maximum cross-correlations” among neighboring electrodes, to find the direction of maximum flow of the codes with lengths less than 8.
Normalized maximum cross-correlations were almost constant irrespective of code.
Furthermore, if the spike trains were shuffled in interval orders or in electrodes, they became significantly small.
Thus, the analysis suggested that local codes of approximately constant shape propagated and conveyed information across the network.
Hence, the codes can serve as visible and trackable marks of propagating spike waves as well as evaluating information flow in the neuronal network.
American Psychological Association (APA)
Tamura, Shinichi& Nishitani, Yoshi& Hosokawa, Chie& Miyoshi, Tomomitsu& Sawai, Hajime& Kamimura, Takuya…[et al.]. 2016. Spike Code Flow in Cultured Neuronal Networks. Computational Intelligence and Neuroscience،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1099749
Modern Language Association (MLA)
Tamura, Shinichi…[et al.]. Spike Code Flow in Cultured Neuronal Networks. Computational Intelligence and Neuroscience Vol. 2016, no. 2016 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1099749
American Medical Association (AMA)
Tamura, Shinichi& Nishitani, Yoshi& Hosokawa, Chie& Miyoshi, Tomomitsu& Sawai, Hajime& Kamimura, Takuya…[et al.]. Spike Code Flow in Cultured Neuronal Networks. Computational Intelligence and Neuroscience. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1099749
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099749