![](/images/graphics-bg.png)
Modern Treatments and Stem Cell Therapies for Perianal Crohn’s Fistulas
Joint Authors
Al-Maawali, Alghalya Khalid Sulaiman
Nguyen, Phuong
Phang, P. Terry
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Crohn’s disease (CD) is a complex disorder with important incidence in North America.
Perianal fistulas occur in about 20% of patients with CD and are almost always classified as complex fistulas.
Conventional treatment options have shown different success rates, yet there are data indicating that these approaches cannot achieve total cure and may not improve quality of life of these patients.
Fibrin glue, fistula plug, topical tacrolimus, local injection of infliximab, and use of hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC) are newly suggested therapies with variable success rates.
Here, we aim to review these novel therapies for the treatment of complex fistulizing CD.
Although initial results are promising, randomized studies are needed to prove efficacy of these approaches in curing fistulizing perianal CD.
American Psychological Association (APA)
Al-Maawali, Alghalya Khalid Sulaiman& Nguyen, Phuong& Phang, P. Terry. 2016. Modern Treatments and Stem Cell Therapies for Perianal Crohn’s Fistulas. Canadian Journal of Gastroenterology and Hepatology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1099839
Modern Language Association (MLA)
Al-Maawali, Alghalya Khalid Sulaiman…[et al.]. Modern Treatments and Stem Cell Therapies for Perianal Crohn’s Fistulas. Canadian Journal of Gastroenterology and Hepatology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1099839
American Medical Association (AMA)
Al-Maawali, Alghalya Khalid Sulaiman& Nguyen, Phuong& Phang, P. Terry. Modern Treatments and Stem Cell Therapies for Perianal Crohn’s Fistulas. Canadian Journal of Gastroenterology and Hepatology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1099839
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099839