Eosinophilic Esophagitis in Children and Adolescents with Abdominal Pain: Comparison with EoE-Dysphagia and Functional Abdominal Pain
Joint Authors
Gunasekaran, Thirumazhisai
Prabhakar, Gautham
Schwartz, Alan
Gorla, Kiranmai
Gupta, Sandeep
Berman, James
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aim.
Compare EoE-AP with EoE-D for clinical, endoscopy (EGD), histology and outcomes and also with FAP-N.
Method.
Symptoms, physical findings, EGD, histology, symptom scores, and treatments were recorded for the three groups.
Cluster analysis was done.
Results.
Dysphagia and abdominal pain were different in numbers but not statistically significant between EoE-AP and EoE-D.
EGD, linear furrows, white exudates were more in the EoE-D and both combined were significant ( p < 0.05 ).
EoE-D, peak and mean eosinophils ( p 0.06 ) and eosinophilic micro abscesses ( p 0.001 ) were higher.
Follow-Up.
Based on single symptom, EoE-AP had 30% ( p 0 .
25 ) improvement, EoE-D 86% ( p < 0.001 ) and similar with composite score ( p 0.57 and <0.001, resp.).
Patients who had follow-up, EGD: 42.8% with EoE-AP and 77.8% with EoE-D, showed single symptom improvement and the eosinophil count fell from 38.5/34.6 (peak and mean) to 31.2/30.4 ( p 0.70 ) and from 43.6/40.8 to 25.2/22.8 ( p < 0.001 ), respectively.
FAP-N patients had similar symptom improvement like EoE-D.
Cluster Analysis.
EoE-AP and FAP-N were similar in clinical features and response to treatment, but EoE-D was distinctly different from EoE-AP and FAP-N.
Conclusion.
Our study demonstrates that EoE-AP and EoE-D have different histology and outcomes.
In addition, EoE-AP has clinical features similar to the FAP-N group.
American Psychological Association (APA)
Gunasekaran, Thirumazhisai& Prabhakar, Gautham& Schwartz, Alan& Gorla, Kiranmai& Gupta, Sandeep& Berman, James. 2016. Eosinophilic Esophagitis in Children and Adolescents with Abdominal Pain: Comparison with EoE-Dysphagia and Functional Abdominal Pain. Canadian Journal of Gastroenterology and Hepatology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1099869
Modern Language Association (MLA)
Gunasekaran, Thirumazhisai…[et al.]. Eosinophilic Esophagitis in Children and Adolescents with Abdominal Pain: Comparison with EoE-Dysphagia and Functional Abdominal Pain. Canadian Journal of Gastroenterology and Hepatology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1099869
American Medical Association (AMA)
Gunasekaran, Thirumazhisai& Prabhakar, Gautham& Schwartz, Alan& Gorla, Kiranmai& Gupta, Sandeep& Berman, James. Eosinophilic Esophagitis in Children and Adolescents with Abdominal Pain: Comparison with EoE-Dysphagia and Functional Abdominal Pain. Canadian Journal of Gastroenterology and Hepatology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1099869
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099869