Functional Capacity, Respiratory Muscle Strength, and Oxygen Consumption Predict Mortality in Patients with Cirrhosis
Joint Authors
Brandão, Ajácio B. M.
Faustini Pereira, José Leonardo
Galant, Lucas Homercher
Rossi, Danusa
Telles da Rosa, Luis Henrique
Garcia, Eduardo
Marroni, Norma Anair Possa
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Liver diseases influence musculoskeletal functions and may negatively affect the exercise capacity of patients with cirrhosis.
Aim.
To test the relationship between the six-minute walk test (6MWT), maximal inspiratory pressure (MIP), and exercise capacity ( V O 2 p e a k ) measures and the survival rate of patients with cirrhosis.
Methods.
This prospective cohort study consisted of 86 patients diagnosed with cirrhosis with the following aetiology: hepatitis C virus (HCV), hepatitis B virus (HBV), and/or alcoholic cirrhosis (AC).
All patients were followed up for three years and submitted to the 6MWT, pressure measurements with a compound gauge, and an exercise test ( V O 2 p e a k ).
Results.
The survival analysis showed that the individuals who covered a distance shorter than 410 m during the 6MWT had a survival rate of 55% compared with a rate of 97% for the individuals who walked more than 410 m ( p = 0.0001).
Individuals with MIPs below −70 cmH2O had a survival rate of 62% compared with a rate of 93% for those with MIPs above −70 cmH2O ( p = 0.0001).
The patients with values below 17 mL/kg had a survival rate of 55% compared with a rate of 94% for those with values above 17 mL/kg ( p = 0.0001).
Conclusion.
The 6MWT distance, MIP, and oxygen consumption are predictors of mortality in patients with cirrhosis.
American Psychological Association (APA)
Faustini Pereira, José Leonardo& Galant, Lucas Homercher& Rossi, Danusa& Telles da Rosa, Luis Henrique& Garcia, Eduardo& Brandão, Ajácio B. M.…[et al.]. 2016. Functional Capacity, Respiratory Muscle Strength, and Oxygen Consumption Predict Mortality in Patients with Cirrhosis. Canadian Journal of Gastroenterology and Hepatology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1099907
Modern Language Association (MLA)
Faustini Pereira, José Leonardo…[et al.]. Functional Capacity, Respiratory Muscle Strength, and Oxygen Consumption Predict Mortality in Patients with Cirrhosis. Canadian Journal of Gastroenterology and Hepatology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1099907
American Medical Association (AMA)
Faustini Pereira, José Leonardo& Galant, Lucas Homercher& Rossi, Danusa& Telles da Rosa, Luis Henrique& Garcia, Eduardo& Brandão, Ajácio B. M.…[et al.]. Functional Capacity, Respiratory Muscle Strength, and Oxygen Consumption Predict Mortality in Patients with Cirrhosis. Canadian Journal of Gastroenterology and Hepatology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1099907
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099907