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Comment on “Evaluation of Antiviral Therapy Performed after Curative Therapy in Patients with HBV-Related Hepatocellular Carcinoma: An Updated Meta-Analysis”
Joint Authors
Mo, Han-Yue
Xiang, Bang-De
Zhong, Jian-Hong
Li, Le-Qun
You, Xue-Mei
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-2, 2 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-14
Country of Publication
Egypt
No. of Pages
2
Main Subjects
Abstract EN
We read with interest the updated meta-analysis by Yuan et al.
[1] which investigated the role of nucleos(t)ide analog (NA) therapy for patients with hepatitis B virus (HBV) related hepatocellular carcinoma (HCC) after surgery.
Even after curative resection or ablation, the incidence of HCC recurrence is very high [2].
However, no adjuvant and/or postoperative therapies with definite efficacy to prevent HCC recurrence are recommended by official guidelines.
HBV is the main cause of HCC in Asia.
In this point, Yuan and coworkers [1] performed an interesting and important updated meta-analysis in order to determine whether antiviral therapy with NA can prevent HCC recurrence and improve patients’ survival after surgery.
Their meta-analysis showed that NA therapy significantly reduced 1- and 3-year recurrence and significantly improved 1-, 3-, and 5-year overall survival and disease-free survival.
We feel that some of these results may need to be treated with caution.
And we would like to propose several important issues raised in this meta-analysis.
American Psychological Association (APA)
Mo, Han-Yue& Xiang, Bang-De& Zhong, Jian-Hong& Li, Le-Qun& You, Xue-Mei. 2016. Comment on “Evaluation of Antiviral Therapy Performed after Curative Therapy in Patients with HBV-Related Hepatocellular Carcinoma: An Updated Meta-Analysis”. Canadian Journal of Gastroenterology and Hepatology،Vol. 2016, no. 2016, pp.1-2.
https://search.emarefa.net/detail/BIM-1099927
Modern Language Association (MLA)
Mo, Han-Yue…[et al.]. Comment on “Evaluation of Antiviral Therapy Performed after Curative Therapy in Patients with HBV-Related Hepatocellular Carcinoma: An Updated Meta-Analysis”. Canadian Journal of Gastroenterology and Hepatology No. 2016 (2016), pp.1-2.
https://search.emarefa.net/detail/BIM-1099927
American Medical Association (AMA)
Mo, Han-Yue& Xiang, Bang-De& Zhong, Jian-Hong& Li, Le-Qun& You, Xue-Mei. Comment on “Evaluation of Antiviral Therapy Performed after Curative Therapy in Patients with HBV-Related Hepatocellular Carcinoma: An Updated Meta-Analysis”. Canadian Journal of Gastroenterology and Hepatology. 2016. Vol. 2016, no. 2016, pp.1-2.
https://search.emarefa.net/detail/BIM-1099927
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099927