CIHR Canadian HIV Trials Network Coinfection and Concurrent Diseases Core Research Group: 2016 Updated Canadian HIVHepatitis C Adult Guidelines for Management and Treatment
Joint Authors
Klein, Marina B.
Shafran, Stephen D.
Hull, Mark
Wong, Alex
Tseng, Alice
Giguère, Pierre
Barrett, Lisa
Haider, Shariq
Conway, Brian
Cooper, Curtis
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-34, 34 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-04
Country of Publication
Egypt
No. of Pages
34
Main Subjects
Abstract EN
Background.
Hepatitis C virus (HCV) coinfection occurs in 20–30% of Canadians living with HIV and is responsible for a heavy burden of morbidity and mortality.
Purpose.
To update national standards for management of HCV-HIV coinfected adults in the Canadian context with evolving evidence for and accessibility of effective and tolerable DAA therapies.
The document addresses patient workup and treatment preparation, antiviral recommendations overall and in specific populations, and drug-drug interactions.
Methods.
A standing working group with HIV-HCV expertise was convened by The Canadian Institute of Health Research HIV Trials Network to review recently published HCV antiviral data and update Canadian HIV-HCV Coinfection Guidelines.
Results.
The gap in sustained virologic response between HCV monoinfection and HIV-HCV coinfection has been eliminated with newer HCV antiviral regimens.
All coinfected individuals should be assessed for interferon-free, Direct Acting Antiviral HCV therapy.
Regimens vary in content, duration, and success based largely on genotype.
Reimbursement restrictions forcing the use of pegylated interferon is not acceptable if optimal patient care is to be provided.
Discussion.
Recommendations may not supersede individual clinical judgement.
Treatment advances published since December 2015 are not considered in this document.
American Psychological Association (APA)
Hull, Mark& Shafran, Stephen D.& Wong, Alex& Tseng, Alice& Giguère, Pierre& Barrett, Lisa…[et al.]. 2016. CIHR Canadian HIV Trials Network Coinfection and Concurrent Diseases Core Research Group: 2016 Updated Canadian HIVHepatitis C Adult Guidelines for Management and Treatment. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2016, no. 2016, pp.1-34.
https://search.emarefa.net/detail/BIM-1099993
Modern Language Association (MLA)
Hull, Mark…[et al.]. CIHR Canadian HIV Trials Network Coinfection and Concurrent Diseases Core Research Group: 2016 Updated Canadian HIVHepatitis C Adult Guidelines for Management and Treatment. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2016 (2016), pp.1-34.
https://search.emarefa.net/detail/BIM-1099993
American Medical Association (AMA)
Hull, Mark& Shafran, Stephen D.& Wong, Alex& Tseng, Alice& Giguère, Pierre& Barrett, Lisa…[et al.]. CIHR Canadian HIV Trials Network Coinfection and Concurrent Diseases Core Research Group: 2016 Updated Canadian HIVHepatitis C Adult Guidelines for Management and Treatment. Canadian Journal of Infectious Diseases and Medical Microbiology. 2016. Vol. 2016, no. 2016, pp.1-34.
https://search.emarefa.net/detail/BIM-1099993
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099993