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Evidence of Hepatitis B Virus Infection in Cancer and Noncancer Stem Cells Associated with Human Hepatocellular Carcinoma
Joint Authors
Minuk, Gerald
Bautista, Wendy
Klein, Julianne
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Both the hepatitis B virus (HBV) and cancer stem cells (CSCs) have been independently implicated in the pathogenesis of hepatocellular carcinoma (HCC).
To date, there have been no reports describing HBV infection within CSCs.
In this report we describe HBV core (HBcAg) and HBx protein expression within CSCs associated with human HCC.
HBV markers were also identified in nonmalignant stem cells present in adjacent nontumor tissue.
These findings provide new insights into the pathogenesis of HBV-induced HCC and are potentially relevant to the treatment of both HCC and chronic HBV.
American Psychological Association (APA)
Minuk, Gerald& Bautista, Wendy& Klein, Julianne. 2016. Evidence of Hepatitis B Virus Infection in Cancer and Noncancer Stem Cells Associated with Human Hepatocellular Carcinoma. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100022
Modern Language Association (MLA)
Minuk, Gerald…[et al.]. Evidence of Hepatitis B Virus Infection in Cancer and Noncancer Stem Cells Associated with Human Hepatocellular Carcinoma. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100022
American Medical Association (AMA)
Minuk, Gerald& Bautista, Wendy& Klein, Julianne. Evidence of Hepatitis B Virus Infection in Cancer and Noncancer Stem Cells Associated with Human Hepatocellular Carcinoma. Canadian Journal of Infectious Diseases and Medical Microbiology. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100022
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100022