Life Threatening Severe QTc Prolongation in Patient with Systemic Lupus Erythematosus due to Hydroxychloroquine
Joint Authors
O’Laughlin, John P.
Mehta, Parag H.
Wong, Brian C.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We present a case of a syncopal episode resulting from significant QT interval prolongation in a patient on hydroxychloroquine for the treatment of systemic lupus erythematosus and end stage renal disease.
The patient had been treated with hydroxychloroquine for two years prior to presentation.
After thorough workup for secondary causes of QT interval prolongation hydroxychloroquine was discontinued and the patient’s QT interval shortened.
The patient was treated with mexiletine to prevent sudden ventricular arrhythmias, which was unique compared to other documented cases in which lidocaine was used.
The patient was noted to have mild prolongation of the QT interval on electrocardiogram prior to initiation of hydroxychloroquine therapy which was exacerbated by its use and may have been caused due to toxicity from underlying renal failure.
American Psychological Association (APA)
O’Laughlin, John P.& Mehta, Parag H.& Wong, Brian C.. 2016. Life Threatening Severe QTc Prolongation in Patient with Systemic Lupus Erythematosus due to Hydroxychloroquine. Case Reports in Cardiology،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100337
Modern Language Association (MLA)
O’Laughlin, John P.…[et al.]. Life Threatening Severe QTc Prolongation in Patient with Systemic Lupus Erythematosus due to Hydroxychloroquine. Case Reports in Cardiology No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100337
American Medical Association (AMA)
O’Laughlin, John P.& Mehta, Parag H.& Wong, Brian C.. Life Threatening Severe QTc Prolongation in Patient with Systemic Lupus Erythematosus due to Hydroxychloroquine. Case Reports in Cardiology. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100337
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100337