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Acute Warfarin Toxicity as Initial Manifestation of Metastatic Liver Disease
Joint Authors
Niazi, Masooma
Lvovsky, Dmitry
Nannaka, Varalaxmi Bhavani
Jani, Nihar
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Near complete infiltration of the liver secondary to metastasis from the head and neck cancer is a rare occurrence.
The prognosis of liver failure associated with malignant infiltration is extremely poor; the survival time of patients is extremely low.
We present a case of acute warfarin toxicity as initial manifestation of metastatic liver disease.
Our patient is a 64-year-old woman presenting with epigastric pain and discomfort, found to have unrecordable International Normalized Ratio.
She rapidly deteriorated with acute respiratory failure requiring mechanical ventilation, profound shock requiring high dose vasopressor infusion, severe coagulopathy, worsening liver enzymes with worsening of lactic acidosis and severe metabolic abnormalities, and refractory to aggressive supportive care and died in less than 48 hours.
Autopsy revealed that >90% of the liver was replaced by tumor masses.
American Psychological Association (APA)
Nannaka, Varalaxmi Bhavani& Jani, Nihar& Niazi, Masooma& Lvovsky, Dmitry. 2016. Acute Warfarin Toxicity as Initial Manifestation of Metastatic Liver Disease. Case Reports in Critical Care،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1100449
Modern Language Association (MLA)
Nannaka, Varalaxmi Bhavani…[et al.]. Acute Warfarin Toxicity as Initial Manifestation of Metastatic Liver Disease. Case Reports in Critical Care No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1100449
American Medical Association (AMA)
Nannaka, Varalaxmi Bhavani& Jani, Nihar& Niazi, Masooma& Lvovsky, Dmitry. Acute Warfarin Toxicity as Initial Manifestation of Metastatic Liver Disease. Case Reports in Critical Care. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1100449
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100449