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Intravenous Vitamin C Administered as Adjunctive Therapy for Recurrent Acute Respiratory Distress Syndrome
Joint Authors
Fisher, Bernard J.
Natarajan, Ramesh
Bharara, Amit
Grossman, Catherine
Grinnan, Daniel
Syed, Aamer
DeWilde, Christine
Fowler, Alpha A. (Berry)
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-07
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
This case report summarizes the first use of intravenous vitamin C employed as an adjunctive interventional agent in the therapy of recurrent acute respiratory distress syndrome (ARDS).
The two episodes of ARDS occurred in a young female patient with Cronkhite-Canada syndrome, a rare, sporadically occurring, noninherited disorder that is characterized by extensive gastrointestinal polyposis and malabsorption.
Prior to the episodes of sepsis, the patient was receiving nutrition via chronic hyperalimentation administered through a long-standing central venous catheter.
The patient became recurrently septic with Gram positive cocci which led to two instances of ARDS.
This report describes the broad-based general critical care of a septic patient with acute respiratory failure that includes fluid resuscitation, broad-spectrum antibiotics, and vasopressor support.
Intravenous vitamin C infused at 50 mg per kilogram body weight every 6 hours for 96 hours was incorporated as an adjunctive agent in the care of this patient.
Vitamin C when used as a parenteral agent in high doses acts “pleiotropically” to attenuate proinflammatory mediator expression, to improve alveolar fluid clearance, and to act as an antioxidant.
American Psychological Association (APA)
Bharara, Amit& Grossman, Catherine& Grinnan, Daniel& Syed, Aamer& Fisher, Bernard J.& DeWilde, Christine…[et al.]. 2016. Intravenous Vitamin C Administered as Adjunctive Therapy for Recurrent Acute Respiratory Distress Syndrome. Case Reports in Critical Care،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100454
Modern Language Association (MLA)
Bharara, Amit…[et al.]. Intravenous Vitamin C Administered as Adjunctive Therapy for Recurrent Acute Respiratory Distress Syndrome. Case Reports in Critical Care No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100454
American Medical Association (AMA)
Bharara, Amit& Grossman, Catherine& Grinnan, Daniel& Syed, Aamer& Fisher, Bernard J.& DeWilde, Christine…[et al.]. Intravenous Vitamin C Administered as Adjunctive Therapy for Recurrent Acute Respiratory Distress Syndrome. Case Reports in Critical Care. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100454
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100454