Sinus Augmentation by Platelet-Rich Fibrin Alone: A Report of Two Cases with Histological Examinations

Abstract EN

In sinus floor augmentation of an atrophic posterior maxilla, platelet-rich fibrin (PRF) has been used as a graft material.

We herein report two cases with histological evaluations of PRF after the surgery.

The first case was a 28-year-old female with an atrophic right posterior maxilla who was treated with sinus floor augmentation and simultaneous implant placement using PRF as the sole graft material in our hospital.

Twenty-four months after surgery, the implant was unfortunately removed because of occlusal overloading by parafunctional habits.

During implant replacement, a tissue sample was obtained from the site of augmentation with PRF and was evaluated histologically.

The second case was a 58-year-old man with severe alveolar atrophy of the right maxilla who underwent lateral sinus augmentation using only PRF in a two-stage procedure in our hospital.

Samples were obtained at the second-stage surgery and histological examinations were performed.

As a result, new bone formation was confirmed histologically in both cases.

Our findings show that the use of PRF as a graft material during sinus floor augmentation induces natural bone regeneration.