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Adalimumab: Another Medication Related to Osteonecrosis of the Jaws?
Joint Authors
Polimeni, Antonella
Terenzi, Valentina
Valentini, Valentino
Cassoni, Andrea
Della Monaca, Marco
Rajabtork Zadeh, Oriana
Raponi, Ingrid
Fadda, Maria Teresa
Umberto, Romeo
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-21
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
The acronym MRONJ has been created in order to identify “Medication-Related Osteonecrosis of the Jaw,” observed after the use of Bisphosphonates, RANK ligand inhibitor, and antiangiogenic medications.
Only a case of osteonecrosis of the jaw in a Chron’s disease patient following a course of Bisphosphonate and Adalimumab therapy has been recently described, so that it has been supposed that also this medication could promote manifestation of osteonecrosis.
Clinical Case.
On August, 2014, a 63-year-old female with a history of idiopathic arthritis treated with medical treatment with Adalimumab from 2010 to 2013 presented referring pain in the right mandible.
Results.
This patient presented with nonexposed osteonecrosis of the jaw after placement, on September, 2010, of four titanium fixtures in the mandible.
Conclusions.
The authors suggest that the biologic therapy with an anti-TNF-α antibody might promote the manifestation of osteonecrosis and compromise oral healing capacity of the bone.
American Psychological Association (APA)
Cassoni, Andrea& Umberto, Romeo& Terenzi, Valentina& Della Monaca, Marco& Rajabtork Zadeh, Oriana& Raponi, Ingrid…[et al.]. 2016. Adalimumab: Another Medication Related to Osteonecrosis of the Jaws?. Case Reports in Dentistry،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1100509
Modern Language Association (MLA)
Cassoni, Andrea…[et al.]. Adalimumab: Another Medication Related to Osteonecrosis of the Jaws?. Case Reports in Dentistry No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1100509
American Medical Association (AMA)
Cassoni, Andrea& Umberto, Romeo& Terenzi, Valentina& Della Monaca, Marco& Rajabtork Zadeh, Oriana& Raponi, Ingrid…[et al.]. Adalimumab: Another Medication Related to Osteonecrosis of the Jaws?. Case Reports in Dentistry. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1100509
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100509