Drug-Induced Hypersensitivity Syndrome Caused by Carbamazepine Used for the Treatment of Trigeminal Neuralgia
Joint Authors
Ono, Yuko
Shimo, Tsuyoshi
Shirafuji, Yoshinori
Hamada, Toshihisa
Masui, Masanori
Obata, Kyoichi
Yao, Mayumi
Kishimoto, Koji
Sasaki, Akira
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-03
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
An 88-year-old man was diagnosed with trigeminal neuralgia, and treatment of carbamazepine 200 mg/day was initiated.
About 6 weeks later, the patient developed a skin rash accompanied by fever.
He was admitted to hospital and diagnosed with drug-induced hypersensitivity syndrome (DIHS) caused by carbamazepine.
Oral carbamazepine treatment was stopped, but blood tests showed acute liver and acute renal failure.
Drug-induced lymphocyte stimulation test (DLST) for carbamazepine, human herpes virus-6 (HHV-6) IgG, and CMV-HRP were negative.
Oral prednisolone therapy was begun 18 days later.
The titer of HHV-6 IgG antibodies was then detected (640 times).
Following treatment, liver and renal function improved and the erythema disappeared.
American Psychological Association (APA)
Ono, Yuko& Shimo, Tsuyoshi& Shirafuji, Yoshinori& Hamada, Toshihisa& Masui, Masanori& Obata, Kyoichi…[et al.]. 2016. Drug-Induced Hypersensitivity Syndrome Caused by Carbamazepine Used for the Treatment of Trigeminal Neuralgia. Case Reports in Dentistry،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100545
Modern Language Association (MLA)
Ono, Yuko…[et al.]. Drug-Induced Hypersensitivity Syndrome Caused by Carbamazepine Used for the Treatment of Trigeminal Neuralgia. Case Reports in Dentistry No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100545
American Medical Association (AMA)
Ono, Yuko& Shimo, Tsuyoshi& Shirafuji, Yoshinori& Hamada, Toshihisa& Masui, Masanori& Obata, Kyoichi…[et al.]. Drug-Induced Hypersensitivity Syndrome Caused by Carbamazepine Used for the Treatment of Trigeminal Neuralgia. Case Reports in Dentistry. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100545
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100545
