Acrokeratosis Paraneoplastica Associated with Cervical Squamous Cell Carcinoma
Joint Authors
Squires, Bryan
Daveluy, Steven D.
Joiner, Michael C.
Hurst, Newton
Bishop, Michael
Miller, Steven R.
Source
Case Reports in Dermatological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-22
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Background.
Acrokeratosis paraneoplastica, or Bazex syndrome, is a paraneoplastic syndrome characterized by cutaneous psoriasiform lesions with associated acral erythema and scale, as well as nail changes, including onycholysis and ungual dystrophy.
Its most advanced, severe form involves the trunk, elbows, and knees.
It is typically associated with upper aerodigestive tract malignancies in males.
Rare cases associated with gynecological cancers have been reported, including uterine adenocarcinoma, as well as ovarian and vulvar squamous cell carcinomas.
Cutaneous manifestations often precede cancer diagnosis.
In most reported cases, skin changes resolve when the underlying malignancy is adequately treated.
Main Observations.
We present the case of a 56-year-old female diagnosed with acrokeratosis paraneoplastica following the discovery of FIGO stage IIB cervical squamous cell carcinoma (SCC).
Scaling, hyperpigmentation, xerosis, and fissuring were noted on the patient’s hands, feet, legs, arms, and lower back.
Pitting was noted on her fingernails.
Her cervical cancer was successfully treated with chemoradiotherapy, after which her cutaneous lesions persisted for two months before resolving.
Conclusions.
The presentation of acrokeratosis paraneoplastica in this context is atypical.
Reports of associations with gynecological cancers, as in our patient’s case, are exceedingly rare.
American Psychological Association (APA)
Squires, Bryan& Daveluy, Steven D.& Joiner, Michael C.& Hurst, Newton& Bishop, Michael& Miller, Steven R.. 2016. Acrokeratosis Paraneoplastica Associated with Cervical Squamous Cell Carcinoma. Case Reports in Dermatological Medicine،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100656
Modern Language Association (MLA)
Squires, Bryan…[et al.]. Acrokeratosis Paraneoplastica Associated with Cervical Squamous Cell Carcinoma. Case Reports in Dermatological Medicine No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1100656
American Medical Association (AMA)
Squires, Bryan& Daveluy, Steven D.& Joiner, Michael C.& Hurst, Newton& Bishop, Michael& Miller, Steven R.. Acrokeratosis Paraneoplastica Associated with Cervical Squamous Cell Carcinoma. Case Reports in Dermatological Medicine. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100656
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100656