A Case of Glucocorticoid Remediable Aldosteronism and Thoracoabdominal Aneurysms
Joint Authors
Shahrrava, Anahita
Moinuddin, Sunnan
Boddu, Prajwal
Shah, Rohan
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-05
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Glucocorticoid remediable aldosteronism (GRA) is rare familial form of primary aldosteronism characterized by a normalization of hypertension with the administration of glucocorticoids.
We present a case of GRA and thoracoabdominal aneurysm complicated by multiple aortic dissections requiring complex surgical and endovascular repairs.
Registry studies have shown a high rate of intracranial aneurysms in GRA patients with high case fatality rates.
The association of thoracoabdominal aneurysms with GRA has not been described, thus far, in literature.
Studies have shown that high tissue aldosterone levels concomitant with salt intake have a significant role in the pathogenesis of aneurysms and this may explain the formation of aneurysms in the intracranial vasculature and aorta.
The association of GRA with thoracic aortic aneurysms needs to be further studied to develop screening recommendations for early identification and optimal treatment.
Also, the early use of mineralocorticoid antagonists may have a significant preventive and attenuating effect in aneurysm formation, an association which needs to be confirmed in future studies.
American Psychological Association (APA)
Shahrrava, Anahita& Moinuddin, Sunnan& Boddu, Prajwal& Shah, Rohan. 2016. A Case of Glucocorticoid Remediable Aldosteronism and Thoracoabdominal Aneurysms. Case Reports in Endocrinology،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100668
Modern Language Association (MLA)
Shahrrava, Anahita…[et al.]. A Case of Glucocorticoid Remediable Aldosteronism and Thoracoabdominal Aneurysms. Case Reports in Endocrinology No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100668
American Medical Association (AMA)
Shahrrava, Anahita& Moinuddin, Sunnan& Boddu, Prajwal& Shah, Rohan. A Case of Glucocorticoid Remediable Aldosteronism and Thoracoabdominal Aneurysms. Case Reports in Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100668
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100668