Gigantomastia and Macroprolactinemia Responding to Cabergoline Treatment: A Case Report and Minireview of the Literature
Joint Authors
Aydin, Cevdet
Ersoy, Reyhan
Cakir, Bekir
Dellal, Fatma Dilek
Kaya, Gulfem
Ozdemir, Didem
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Macroprolactinemia is defined as predominance of high molecular weight prolactin forms in the circulation.
Although macroprolactin is considered as a biologically inactive molecule, some authorities suggest treatment in symptomatic cases.
Gigantomastia is defined as excess breast tissue and most cases in the literature were treated by surgical intervention.
Case.
A 44-year-old woman was admitted to our clinic with gigantomastia and galactorrhea.
The patient had a demand for surgical therapy.
In laboratory examination, she had hyperprolactinemia and macroprolactinemia.
Pituitary imaging revealed 6 mm microadenoma in right side of the hypophysis.
Since she was symptomatic, cabergolin treatment was started.
Macroprolactin became negative, breast circumference decreased significantly, and galactorrhea resolved after treatment.
Conclusion.
Gigantomastia might be the presenting symptom in patients with macroprolactinemia.
In these patients medical treatment with cabergoline may be used initially as an alternative to surgical approach.
American Psychological Association (APA)
Dellal, Fatma Dilek& Ozdemir, Didem& Aydin, Cevdet& Kaya, Gulfem& Ersoy, Reyhan& Cakir, Bekir. 2016. Gigantomastia and Macroprolactinemia Responding to Cabergoline Treatment: A Case Report and Minireview of the Literature. Case Reports in Endocrinology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1100681
Modern Language Association (MLA)
Dellal, Fatma Dilek…[et al.]. Gigantomastia and Macroprolactinemia Responding to Cabergoline Treatment: A Case Report and Minireview of the Literature. Case Reports in Endocrinology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1100681
American Medical Association (AMA)
Dellal, Fatma Dilek& Ozdemir, Didem& Aydin, Cevdet& Kaya, Gulfem& Ersoy, Reyhan& Cakir, Bekir. Gigantomastia and Macroprolactinemia Responding to Cabergoline Treatment: A Case Report and Minireview of the Literature. Case Reports in Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1100681
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100681