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Clinical Heterogeneity of Guillain-Barré Syndrome in the Emergency Department: Impact on Clinical Outcome
Joint Authors
Papathanasiou, Athanasios
Markakis, Ioannis
Source
Case Reports in Emergency Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-27
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Guillain-Barré syndrome (GBS) is mainly classified into acute inflammatory demyelinating polyneuropathy (AIDP) and acute motor axonal neuropathy (AMAN).
Although diagnosis of GBS requires progressive weakness and universal areflexia or hyporeflexia, cases of GBS with preserved or increased deep tendon reflexes (DTRs) have been increasingly recognized.
We report three cases of GBS, presenting at a single unit in six months.
Our first case presented with pure sensory symptoms.
The second case had nonspecific generalized weakness, while the third presented with typical ascending weakness.
One of our patients had preserved DTRs, while the other two had increased DTRs.
Our two cases with hyperreflexia were found to have a preceding Campylobacter jejuni infection and anti-ganglioside antibodies, and their electrophysiological studies revealed AMAN.
The other case had an AIDP.
Only one case was offered a diagnosis and treatment from the first emergency department (ED) visit and had a better clinical outcome.
Clinical diagnosis of GBS in the ED can be challenging.
Delay in diagnosis of GBS in the ED is common due to cases with intact or increased DTRs, atypical pattern of weakness, or pure sensory symptoms.
Emergency physicians should be aware of GBS clinical heterogeneity, because early diagnosis and treatment improve clinical outcome.
American Psychological Association (APA)
Papathanasiou, Athanasios& Markakis, Ioannis. 2016. Clinical Heterogeneity of Guillain-Barré Syndrome in the Emergency Department: Impact on Clinical Outcome. Case Reports in Emergency Medicine،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100726
Modern Language Association (MLA)
Papathanasiou, Athanasios& Markakis, Ioannis. Clinical Heterogeneity of Guillain-Barré Syndrome in the Emergency Department: Impact on Clinical Outcome. Case Reports in Emergency Medicine No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1100726
American Medical Association (AMA)
Papathanasiou, Athanasios& Markakis, Ioannis. Clinical Heterogeneity of Guillain-Barré Syndrome in the Emergency Department: Impact on Clinical Outcome. Case Reports in Emergency Medicine. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100726
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100726