Spider Bite: A Rare Case of Acute Necrotic Arachnidism with Rapid and Fatal Evolution
Joint Authors
Pezzi, Mario
Scozzafava, Annamaria
Verre, Mario
Giglio, Anna Maria
Filippelli, Orazio
Serafino, Giuseppe
Source
Case Reports in Emergency Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The spider bites are quite frequent and often resolve quickly without leaving outcomes; only some species are capable of causing necrotic and systematic lesions in humans.
Among them, we should mention the genus Loxosceles.
The venom released from the spider bite of Loxosceles species is composed of proteins, enzymes, and nonenzymatic polypeptides.
The phospholipase D family was identified as the active component of the venom.
This family of enzymes is responsible for the local and systemic effects observed in loxoscelism.
Phospholipases D interact with cell membranes triggering alterations which involve the complement system and activation of neutrophils and they cause the dermonecrotic skin lesions and systemic effects.
We describe a fatal case of acute intoxication caused by a spider bite probably belonging to the species Loxosceles.
The initial lesion was localized to a finger of a hand.
Clinical course was worsening with deep necrotic lesions on limb, shock, hemolysis, acute kidney failure, and disseminated intravascular coagulation.
All therapies were ineffective.
This is the first fatal case described in Europe.
American Psychological Association (APA)
Pezzi, Mario& Giglio, Anna Maria& Scozzafava, Annamaria& Filippelli, Orazio& Serafino, Giuseppe& Verre, Mario. 2016. Spider Bite: A Rare Case of Acute Necrotic Arachnidism with Rapid and Fatal Evolution. Case Reports in Emergency Medicine،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100738
Modern Language Association (MLA)
Pezzi, Mario…[et al.]. Spider Bite: A Rare Case of Acute Necrotic Arachnidism with Rapid and Fatal Evolution. Case Reports in Emergency Medicine No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100738
American Medical Association (AMA)
Pezzi, Mario& Giglio, Anna Maria& Scozzafava, Annamaria& Filippelli, Orazio& Serafino, Giuseppe& Verre, Mario. Spider Bite: A Rare Case of Acute Necrotic Arachnidism with Rapid and Fatal Evolution. Case Reports in Emergency Medicine. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100738
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100738