Use of Aldosterone Antagonist to Treat Diarrhea and Hypokalemia of Ogilvie’s Syndrome
Joint Authors
Ram, Pradhum
Goyal, Abhinav
Lu, Marvin
Sloan, Joshua
McElhaugh, William
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-12
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Ogilvie’s syndrome (OS) is a functional obstruction of the bowel due to an autonomic imbalance.
It often presents with diarrhea and is associated with hypokalemia.
We present a case of a 70-year-old male who developed severe abdominal distension, watery diarrhea, and persistent hypokalemia status after left hip arthroplasty after suffering from a femoral neck fracture due to a fall and was diagnosed with OS.
The persistent hypokalemia was slow to improve despite aggressive repletion because of the high potassium losses in the stool.
This is most likely mediated through the increased expression of BK channels in the colonic mucosa.
Aldosterone is theorized to have a role in the regulation of BK channels.
Spironolactone was subsequently given and resulted in marked improvement of the diarrhea and hypokalemia.
Thus, this case suggests a novel therapeutic approach for the treatment of Ogilvie’s syndrome-associated diarrhea and hypokalemia.
American Psychological Association (APA)
Ram, Pradhum& Goyal, Abhinav& Lu, Marvin& Sloan, Joshua& McElhaugh, William. 2016. Use of Aldosterone Antagonist to Treat Diarrhea and Hypokalemia of Ogilvie’s Syndrome. Case Reports in Gastrointestinal Medicine،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100766
Modern Language Association (MLA)
Ram, Pradhum…[et al.]. Use of Aldosterone Antagonist to Treat Diarrhea and Hypokalemia of Ogilvie’s Syndrome. Case Reports in Gastrointestinal Medicine No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1100766
American Medical Association (AMA)
Ram, Pradhum& Goyal, Abhinav& Lu, Marvin& Sloan, Joshua& McElhaugh, William. Use of Aldosterone Antagonist to Treat Diarrhea and Hypokalemia of Ogilvie’s Syndrome. Case Reports in Gastrointestinal Medicine. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100766
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100766