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Reactivation of Pulmonary Tuberculosis following Treatment of Myelofibrosis with Ruxolitinib
Joint Authors
Abidi, Maheen Z.
Dhakal, Binod
Haque, Javeria
Varma, Parvathi
Olteanu, Horatiu
Guru Murthy, Guru Subramanian
Hari, Parameswaran
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-23
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Ruxolitinib is widely in use for treatment of myeloproliferative disorders.
It causes inhibition of the Janus kinase (JAK) signal transducer and activation of transcription (STAT) pathway, which plays a key role in the underlying pathophysiology of myeloproliferative diseases.
We describe a case of reactivation pulmonary tuberculosis in a retired physician while on treatment with ruxolitinib.
We also review the literature on opportunistic infections following use of ruxolitinib.
Our case highlights the importance of screening for latent tuberculosis in patients from highly endemic areas prior to start of therapy with ruxolitinib.
American Psychological Association (APA)
Abidi, Maheen Z.& Haque, Javeria& Varma, Parvathi& Olteanu, Horatiu& Guru Murthy, Guru Subramanian& Dhakal, Binod…[et al.]. 2016. Reactivation of Pulmonary Tuberculosis following Treatment of Myelofibrosis with Ruxolitinib. Case Reports in Hematology،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100839
Modern Language Association (MLA)
Abidi, Maheen Z.…[et al.]. Reactivation of Pulmonary Tuberculosis following Treatment of Myelofibrosis with Ruxolitinib. Case Reports in Hematology No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100839
American Medical Association (AMA)
Abidi, Maheen Z.& Haque, Javeria& Varma, Parvathi& Olteanu, Horatiu& Guru Murthy, Guru Subramanian& Dhakal, Binod…[et al.]. Reactivation of Pulmonary Tuberculosis following Treatment of Myelofibrosis with Ruxolitinib. Case Reports in Hematology. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100839
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100839