Chronic Disseminated Candidiasis Complicated by Immune Reconstitution Inflammatory Syndrome in Child with Acute Lymphoblastic Leukemia
Joint Authors
Zając-Spychała, Olga
Ukielska, Bogna
Jończyk-Potoczna, Katarzyna
Konatkowska, Benigna
Wachowiak, Jacek
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Hepatosplenic candidiasis also known as chronic disseminated candidiasis is a rare manifestation of invasive fungal infection typically observed in patients with acute leukemia in prolonged, deep neutropenia.
Immune reconstitution inflammatory syndrome (IRIS) is an inflammatory disorder triggered by rapid resolution of neutropenia.
Diagnosis and treatment of IRIS are still challenging due to a variety of clinical symptoms, lack of certain diagnostic criteria, and no standards of treatment.
The diagnosis of IRIS is even more difficult in patients with hematological malignancies complicated by “probable” invasive fungal infection, when fungal pathogen is still uncertain.
We report a case of probable hepatic candidiasis in 4-year-old boy with acute lymphoblastic leukemia.
Despite proper antifungal therapy, there was no clinical and radiological improvement, so diagnosis of Candida-related IRIS was made and corticosteroid therapy was added to antifungal treatment achieving prompt resolution of infection symptoms.
American Psychological Association (APA)
Zając-Spychała, Olga& Ukielska, Bogna& Jończyk-Potoczna, Katarzyna& Konatkowska, Benigna& Wachowiak, Jacek. 2016. Chronic Disseminated Candidiasis Complicated by Immune Reconstitution Inflammatory Syndrome in Child with Acute Lymphoblastic Leukemia. Case Reports in Hematology،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100863
Modern Language Association (MLA)
Zając-Spychała, Olga…[et al.]. Chronic Disseminated Candidiasis Complicated by Immune Reconstitution Inflammatory Syndrome in Child with Acute Lymphoblastic Leukemia. Case Reports in Hematology No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100863
American Medical Association (AMA)
Zając-Spychała, Olga& Ukielska, Bogna& Jończyk-Potoczna, Katarzyna& Konatkowska, Benigna& Wachowiak, Jacek. Chronic Disseminated Candidiasis Complicated by Immune Reconstitution Inflammatory Syndrome in Child with Acute Lymphoblastic Leukemia. Case Reports in Hematology. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100863
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100863