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Attempted Suicide by Massive Warfarin Ingestion Conservatively Managed Using Phytonadione
Joint Authors
Twilla, Jennifer D.
March, Katherine L.
Patel, Kruti S.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-04
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Treatment strategies for acute toxicity following massive ingestion of warfarin are not well described in the literature.
Warfarin is the primary oral anticoagulation agent used in the treatment of thromboembolic disease, and patients with acute toxicity are at risk for life-threatening hemorrhages.
Treatment options include phytonadione (vitamin K1), fresh frozen plasma (FFP), and prothrombin complex concentrates (PCCs) used alone or in combination.
FFP and PCC can be associated with volume complications, undesirable thromboembolic events, and increased costs.
We describe the case of a 63-year-old female with acute warfarin toxicity following a massive ingestion of warfarin (420 mg–450 mg) in an attempt to commit suicide.
Upon arrival to the emergency department, serial INR checks were initiated to help guide dosing strategy and later adjusted based on INR response to treatment using only phytonadione.
American Psychological Association (APA)
March, Katherine L.& Patel, Kruti S.& Twilla, Jennifer D.. 2016. Attempted Suicide by Massive Warfarin Ingestion Conservatively Managed Using Phytonadione. Case Reports in Hematology،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100874
Modern Language Association (MLA)
March, Katherine L.…[et al.]. Attempted Suicide by Massive Warfarin Ingestion Conservatively Managed Using Phytonadione. Case Reports in Hematology No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1100874
American Medical Association (AMA)
March, Katherine L.& Patel, Kruti S.& Twilla, Jennifer D.. Attempted Suicide by Massive Warfarin Ingestion Conservatively Managed Using Phytonadione. Case Reports in Hematology. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100874
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100874