Extra-Adrenal Myelolipoma Containing Small Lymphocytic LymphomaChronic Lymphocytic Leukemia: A Case Report and Review of the Literature

Abstract EN

Myelolipoma is a benign tumor consisting of mature fat interspersed with hematopoietic elements resembling bone marrow.

The vast majority occurs within the adrenal glands, but several cases of extra-adrenal myelolipomas (EAMLs) have been reported.

We report a case of a 64-year-old male who presented with complaint of lower abdominal discomfort.

CT scan of abdomen and pelvis showed a 6 cm × 5 cm, well-circumscribed, predominantly fatty mass in the presacral region.

Histological examination of the pelvic mass revealed a myelolipoma heavily infiltrated by small lymphoid cell aggregates with immunophenotypic features of small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL).

Review of the literature revealed that there is only one published report of SLL/CLL involving a myelolipoma, which was also an extra-adrenal myelolipoma, and, therefore, our case is the second case of a SLL/CLL involving a myelolipoma that is an extra-adrenal myelolipoma.

Extra-adrenal myelolipomas seem to the preferred myelolipomas for involvement by SLL/CLL.