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Herpes Simplex Virus Hepatitis in an Immunocompetent Host Resembling Hepatic Pyogenic Abscesses
Joint Authors
Down, Carrie
Mehta, Amit
Salama, Gayle
Hissong, Erika
Rosenblatt, Russell
Cantor, Michael
Helfgott, David
Marks, Kristen
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-30
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Herpes simplex virus (HSV) hepatitis represents a rare complication of HSV infection, which can progress to acute liver failure and, in some cases, death.
We describe an immunocompetent 67-year-old male who presented with one week of fever and abdominal pain.
Computed tomography (CT) scan and magnetic resonance imaging (MRI) of the abdomen showed multiple bilobar hepatic lesions, some with rim enhancement, compatible with liver abscesses.
Subsequent liver biopsy, however, revealed hepatocellular necrosis, HSV-type intranuclear inclusions, and immunostaining positive for herpes virus type 2 (HSV-2).
Though initially treated with broad-spectrum antibiotics, following histologic diagnosis of HSV hepatitis, the patient was transitioned to intravenous acyclovir for four weeks and he achieved full clinical recovery.
Given its high mortality and nonspecific presentation, one should consider HSV hepatitis in all patients with acute hepatitis with multifocal hepatic lesions of unknown etiology.
Of special note, this is only the second reported case of HSV liver lesions mimicking pyogenic abscesses on CT and MRI.
American Psychological Association (APA)
Down, Carrie& Mehta, Amit& Salama, Gayle& Hissong, Erika& Rosenblatt, Russell& Cantor, Michael…[et al.]. 2016. Herpes Simplex Virus Hepatitis in an Immunocompetent Host Resembling Hepatic Pyogenic Abscesses. Case Reports in Hepatology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1100917
Modern Language Association (MLA)
Down, Carrie…[et al.]. Herpes Simplex Virus Hepatitis in an Immunocompetent Host Resembling Hepatic Pyogenic Abscesses. Case Reports in Hepatology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1100917
American Medical Association (AMA)
Down, Carrie& Mehta, Amit& Salama, Gayle& Hissong, Erika& Rosenblatt, Russell& Cantor, Michael…[et al.]. Herpes Simplex Virus Hepatitis in an Immunocompetent Host Resembling Hepatic Pyogenic Abscesses. Case Reports in Hepatology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1100917
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100917