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Histoplasmosis-Induced Hemophagocytic Lymphohistiocytosis in an Adult Patient: A Case Report and Review of the Literature
Joint Authors
Untanu, Ramona Vesna
Akbar, Syed
Graziano, Stephen
Vajpayee, Neerja
Source
Case Reports in Infectious Diseases
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life-threating immune dysregulation syndrome characterized by persistent activation of the mononuclear phagocytic system leading to uncontrolled systemic hyperinflammatory response.
The proliferation and activation of histiocytes and lymphocytes lead to production of large amounts of cytokines, also called cytokine storm.
Hematopoietic and lymphoid tissues are directly involved while other organs are damaged by circulating cytokines.
Primary HLH is attributed to genetic defects of the immune system and secondary HLH is usually seen in adults secondary to malignancy, infection, or autoimmune diseases.
Zoonotic diseases including fungal infections are an important cause of HLH.
Secondary HLH can delay the recognition of the underlying zoonoses.
We report the case of a 61-year-old female with history of rheumatoid arthritis with histoplasmosis associated hemophagocytic lymphohistiocytosis.
American Psychological Association (APA)
Untanu, Ramona Vesna& Akbar, Syed& Graziano, Stephen& Vajpayee, Neerja. 2016. Histoplasmosis-Induced Hemophagocytic Lymphohistiocytosis in an Adult Patient: A Case Report and Review of the Literature. Case Reports in Infectious Diseases،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1100934
Modern Language Association (MLA)
Untanu, Ramona Vesna…[et al.]. Histoplasmosis-Induced Hemophagocytic Lymphohistiocytosis in an Adult Patient: A Case Report and Review of the Literature. Case Reports in Infectious Diseases No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1100934
American Medical Association (AMA)
Untanu, Ramona Vesna& Akbar, Syed& Graziano, Stephen& Vajpayee, Neerja. Histoplasmosis-Induced Hemophagocytic Lymphohistiocytosis in an Adult Patient: A Case Report and Review of the Literature. Case Reports in Infectious Diseases. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1100934
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100934