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Direct Acting Antivirals in Patients with Chronic Hepatitis C and Down Syndrome
Joint Authors
Yoo, Eric R.
Perumpail, Ryan B.
Cholankeril, George
Ahmed, Aijaz
Source
Case Reports in Infectious Diseases
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-26
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Patients with Down syndrome who received blood transfusions, likely in conjunction with cardiothoracic surgery for congenital heart disease and prior to the implementation of blood-donor screening for hepatitis C virus infection, face a substantial risk of acquiring the infection.
In the past, interferon-based therapy for chronic hepatitis C infection in patients with Down syndrome was noted to have lower efficacy and potentially higher risk of adverse effects.
Recently, the treatment for chronic hepatitis C has been revolutionized with the introduction of interferon-free direct acting antivirals with favorable safety, tolerability, and efficacy profile.
Based on our experiences, the newly approved sofosbuvir-based direct acting antiviral therapy is well tolerated and highly efficacious in this subpopulation of hepatitis C virus infected patients with Down syndrome.
American Psychological Association (APA)
Yoo, Eric R.& Perumpail, Ryan B.& Cholankeril, George& Ahmed, Aijaz. 2016. Direct Acting Antivirals in Patients with Chronic Hepatitis C and Down Syndrome. Case Reports in Infectious Diseases،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100954
Modern Language Association (MLA)
Yoo, Eric R.…[et al.]. Direct Acting Antivirals in Patients with Chronic Hepatitis C and Down Syndrome. Case Reports in Infectious Diseases No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1100954
American Medical Association (AMA)
Yoo, Eric R.& Perumpail, Ryan B.& Cholankeril, George& Ahmed, Aijaz. Direct Acting Antivirals in Patients with Chronic Hepatitis C and Down Syndrome. Case Reports in Infectious Diseases. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100954
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100954