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A Case of Fluoroquinolone-Resistant Leprosy Discovered after 9 Years of Misdiagnosis
Joint Authors
Sendrasoa, F. A.
Ranaivo, I. M.
Raharolahy, O.
Andrianarison, M.
Ramarozatovo, L. S.
Rakoto-Andrianarivelo, Mala
Cambau, Emmanuelle
Rabenja, Fahafahantsoa Rapelanoro
Source
Case Reports in Infectious Diseases
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-07
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We report a case of misdiagnosed leprosy in a 21-year-old Malagasy male, who, improperly treated, developed secondary mycobacterial resistance to fluoroquinolone.
The patient contracted the infection 9 years prior to the current consultation, displaying on the right thigh a single papulonodular lesion, which progressively spread to the lower leg, back, and face.
Initial administration of ciprofloxacin and prednisolone led to temporary and fluctuating improvement.
Subsequent long-term self-medication with ciprofloxacin and corticosteroid did not heal the foul and nonhealing ulcers on the legs and under the right sole.
Histopathological findings were compatible with lepromatous leprosy.
Skin biopsy was positive for acid-fast bacilli and PCR assay confirmed the presence of a fluoroquinolone-resistant strain of Mycobacterium leprae (gyrA A91V).
After 6 months of standard regimen with rifampicin, clofazimine, and dapsone, clinical outcome significantly improved.
Clinical characteristics and possible epidemiological implications are discussed.
American Psychological Association (APA)
Raharolahy, O.& Ramarozatovo, L. S.& Ranaivo, I. M.& Sendrasoa, F. A.& Andrianarison, M.& Rakoto-Andrianarivelo, Mala…[et al.]. 2016. A Case of Fluoroquinolone-Resistant Leprosy Discovered after 9 Years of Misdiagnosis. Case Reports in Infectious Diseases،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100978
Modern Language Association (MLA)
Raharolahy, O.…[et al.]. A Case of Fluoroquinolone-Resistant Leprosy Discovered after 9 Years of Misdiagnosis. Case Reports in Infectious Diseases No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100978
American Medical Association (AMA)
Raharolahy, O.& Ramarozatovo, L. S.& Ranaivo, I. M.& Sendrasoa, F. A.& Andrianarison, M.& Rakoto-Andrianarivelo, Mala…[et al.]. A Case of Fluoroquinolone-Resistant Leprosy Discovered after 9 Years of Misdiagnosis. Case Reports in Infectious Diseases. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100978
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100978