Simultaneous Two-Vessel Subacute Stent Thrombosis Caused by Clopidogrel Resistance from CYP2C19 Polymorphism
Joint Authors
Afzal, Ashwad
Patel, Bimal
Patel, Neel
Sattur, Sudhakar
Patel, Vinod
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-31
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Clopidogrel resistance from CYP2C19 polymorphism has been associated with stent thrombosis in patients undergoing percutaneous coronary intervention with drug-eluting stents.
We present a case of a 76-year-old male who received drug-eluting stents to the right coronary artery and left anterior descending artery for non-ST elevation myocardial infarction and was discharged on dual antiplatelet therapy with aspirin and clopidogrel.
He subsequently presented with chest pain from anterior, anteroseptal, and inferior ST segment elevation myocardial infarction.
An emergent coronary angiogram revealed acute stent thrombosis with 100% occlusion of RCA and LAD that was successfully treated with thrombus aspiration and angioplasty.
Although he was compliant with his dual antiplatelet therapy, he developed stent thrombosis, which was confirmed as clopidogrel resistance from homozygous CYP2C19 polymorphism.
American Psychological Association (APA)
Afzal, Ashwad& Patel, Bimal& Patel, Neel& Sattur, Sudhakar& Patel, Vinod. 2016. Simultaneous Two-Vessel Subacute Stent Thrombosis Caused by Clopidogrel Resistance from CYP2C19 Polymorphism. Case Reports in Medicine،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101066
Modern Language Association (MLA)
Afzal, Ashwad…[et al.]. Simultaneous Two-Vessel Subacute Stent Thrombosis Caused by Clopidogrel Resistance from CYP2C19 Polymorphism. Case Reports in Medicine No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1101066
American Medical Association (AMA)
Afzal, Ashwad& Patel, Bimal& Patel, Neel& Sattur, Sudhakar& Patel, Vinod. Simultaneous Two-Vessel Subacute Stent Thrombosis Caused by Clopidogrel Resistance from CYP2C19 Polymorphism. Case Reports in Medicine. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101066
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101066
