Hyperammonemia: What Urea-lly Need to Know: Case Report of Severe Noncirrhotic Hyperammonemic Encephalopathy and Review of the Literature
Joint Authors
Upadhyay, Ruby
Bleck, Thomas P.
Busl, Katharina M.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-21
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
A 66-year-old man who presented with coma was found to have isolated severe hyperammonemia and diagnosed with a late-onset urea-cycle disorder.
He was treated successfully and had full recovery.
Methods.
We report a novel case of noncirrhotic hyperammonemia and review the literature on this topic.
Selected literature for review included English-language articles concerning hyperammonemia using the search terms “hyperammonemic encephalopathy”, “non-cirrhotic encephalopathy”, “hepatic encephalopathy”, “urea-cycle disorders”, “ornithine transcarbamylase (OTC) deficiency”, and “fulminant hepatic failure”.
Results.
A unique case of isolated hyperammonemia diagnosed as late-onset OTC deficiency is presented.
Existing evidence about hyperammonemia is organized to address pathophysiology, clinical presentation, diagnosis, and treatment.
The case report is discussed in context of the reviewed literature.
Conclusion.
Late-onset OTC deficiency presenting with severe hyperammonemic encephalopathy and extensive imaging correlate can be fully reversible if recognized promptly and treated aggressively.
American Psychological Association (APA)
Upadhyay, Ruby& Bleck, Thomas P.& Busl, Katharina M.. 2016. Hyperammonemia: What Urea-lly Need to Know: Case Report of Severe Noncirrhotic Hyperammonemic Encephalopathy and Review of the Literature. Case Reports in Medicine،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1101175
Modern Language Association (MLA)
Upadhyay, Ruby…[et al.]. Hyperammonemia: What Urea-lly Need to Know: Case Report of Severe Noncirrhotic Hyperammonemic Encephalopathy and Review of the Literature. Case Reports in Medicine No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1101175
American Medical Association (AMA)
Upadhyay, Ruby& Bleck, Thomas P.& Busl, Katharina M.. Hyperammonemia: What Urea-lly Need to Know: Case Report of Severe Noncirrhotic Hyperammonemic Encephalopathy and Review of the Literature. Case Reports in Medicine. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1101175
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101175