Angioimmunoblastic T Cell Lymphoma Mimicking Chronic Urticaria

Abstract EN

Angioimmunoblastic T cell lymphoma (AITL) is a rare but distinct type of T cell lymphoma with an aggressive course and high mortality.

Most patients are diagnosed late in the disease and usually present with generalized lymphadenopathy.

A minority have skin lesions at the time of diagnosis, more commonly in the form of nonspecific maculopapular rash with or without pruritus.

We report a rare case of AITL presenting with chronic, recurrent angioedema and urticaria-like lesions and no palpable peripheral adenopathy.

Primary Care physicians, dermatologists, and allergists must maintain a high index of suspicion for cutaneous manifestations of lymphoma, especially if the skin lesions are refractory to standard treatment.

Timely diagnosis is essential to improve survival.