A Case Report of Neurosarcoidosis Presenting as a Lymphoma Mimic
Joint Authors
Kaur, Gurcharanjeet
Cameron, Lauren
Syritsyna, Olga
Coyle, Patricia
Kowalska, Agnes
Source
Case Reports in Neurological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-12
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Objective.
To describe a unique presentation of neurosarcoidosis.
Background.
Central nervous system involvement is rare in sarcoidosis.
Sarcoidosis can be severe and can be mistaken for systemic lymphoma.
Case Description.
A 55-year-old right-handed white male with past medical history of obstructive sleep apnea, Raynaud’s disease, and Hashimoto’s thyroiditis was noted to have cognitive decline over a duration of few weeks and 20 lb weight loss.
His neurologic exam (including cranial nerves) was normal except for five-minute recall.
Head CT revealed a lacrimal gland mass, confirmed on brain MRI, which was suspicious for lymphoma on brain PET/MRI.
Subsequent whole-body FDG PET/CT scan showed multiple enlarged lymph nodes.
Bone marrow biopsy was negative.
Serum and CSF ACE levels were within normal limits.
Supraclavicular lymph node biopsy before steroids therapy was initiated and revealed multiple noncaseating granulomas, diagnostic of “sarcoidosis.” He was treated with daily prednisone for two months, followed by weekly infliximab.
Brain MRI two months after treatment with prednisone showed decrease in size of lacrimal lesion, and brain PET/MRI showed normal brain metabolism pattern after five months.
Neurocognitive evaluation three months after diagnosis demonstrated improvements in memory abilities.
Discussion.
Both clinically and radiographically, neurosarcoidosis can mimic systemic lymphoma.
Biopsy in these types of cases is necessary to establish the diagnosis.
American Psychological Association (APA)
Kaur, Gurcharanjeet& Cameron, Lauren& Syritsyna, Olga& Coyle, Patricia& Kowalska, Agnes. 2016. A Case Report of Neurosarcoidosis Presenting as a Lymphoma Mimic. Case Reports in Neurological Medicine،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101316
Modern Language Association (MLA)
Kaur, Gurcharanjeet…[et al.]. A Case Report of Neurosarcoidosis Presenting as a Lymphoma Mimic. Case Reports in Neurological Medicine No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1101316
American Medical Association (AMA)
Kaur, Gurcharanjeet& Cameron, Lauren& Syritsyna, Olga& Coyle, Patricia& Kowalska, Agnes. A Case Report of Neurosarcoidosis Presenting as a Lymphoma Mimic. Case Reports in Neurological Medicine. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101316
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101316