Histiocytic Sarcoma Associated with Coombs Negative Acute Hemolytic Anemia: A Rare Presentation
Joint Authors
Nassiri, Mehdi
Batra, Sandeep
Martin, Stephen C.
Qureshi, Amna
Markel, Troy A.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Histiocytic sarcoma (HS) rarely involves extranodal sites, such as the spleen.
We report a unique pediatric case of massive splenomegaly and refractory Coombs negative hemolytic anemia (CNHA) secondary to HS.
The CNHA resolved completely after an emergent splenectomy.
Next generation sequencing (NGS) revealed novel ASXL1, PTPN11, KIT, and TP53 mutations, unmasking a clonal heterogeneity within the same neoplasm.
American Psychological Association (APA)
Batra, Sandeep& Martin, Stephen C.& Nassiri, Mehdi& Qureshi, Amna& Markel, Troy A.. 2016. Histiocytic Sarcoma Associated with Coombs Negative Acute Hemolytic Anemia: A Rare Presentation. Case Reports in Oncological Medicine،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1101672
Modern Language Association (MLA)
Batra, Sandeep…[et al.]. Histiocytic Sarcoma Associated with Coombs Negative Acute Hemolytic Anemia: A Rare Presentation. Case Reports in Oncological Medicine No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1101672
American Medical Association (AMA)
Batra, Sandeep& Martin, Stephen C.& Nassiri, Mehdi& Qureshi, Amna& Markel, Troy A.. Histiocytic Sarcoma Associated with Coombs Negative Acute Hemolytic Anemia: A Rare Presentation. Case Reports in Oncological Medicine. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1101672
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101672
