An Unusual Cause of Subacute Headache in a Patient Undergoing Chemotherapy for Advanced Testicular Nonseminomatous Germ Cell Tumour
Joint Authors
Clarke, Helen M.
Rao, Ankit R.
Porfiri, Emilio
Source
Case Reports in Oncological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-21
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Testicular (germ cell) cancer is a model of a chemocurable malignancy and tends to have a favourable prognosis even in advanced stages due to exquisite sensitivity to platinum-based chemotherapy.
However, both acute and longer-term toxicities of multiagent chemotherapy remain significant as causes of morbidity, very occasionally mortality, and impaired quality-of-life.
Here, we report a case of acute cerebral venous sinus thrombosis occurring within 10 days of chemotherapy initiation in a young patient without comorbidities, whose only predisposing factors were malignancy, chemotherapy, and perhaps mild dehydration.
The clinical presentation was also unusual with headache of moderate severity only without focal or global neurologic deficits.
We suspect that cisplatin may have had direct vasculotoxic effects.
The patient recovered fully after short-duration anticoagulation but oncologists must remain aware of unusual and unpredictable complications of cytotoxic treatment.
American Psychological Association (APA)
Clarke, Helen M.& Rao, Ankit R.& Porfiri, Emilio. 2016. An Unusual Cause of Subacute Headache in a Patient Undergoing Chemotherapy for Advanced Testicular Nonseminomatous Germ Cell Tumour. Case Reports in Oncological Medicine،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101678
Modern Language Association (MLA)
Clarke, Helen M.…[et al.]. An Unusual Cause of Subacute Headache in a Patient Undergoing Chemotherapy for Advanced Testicular Nonseminomatous Germ Cell Tumour. Case Reports in Oncological Medicine No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1101678
American Medical Association (AMA)
Clarke, Helen M.& Rao, Ankit R.& Porfiri, Emilio. An Unusual Cause of Subacute Headache in a Patient Undergoing Chemotherapy for Advanced Testicular Nonseminomatous Germ Cell Tumour. Case Reports in Oncological Medicine. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101678
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101678