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Scrotal Involvement with Testicular Nonseminomatous Germ Cell Tumour
Joint Authors
O’Leary, C. G.
Allen, J. A.
O’Brien, F.
Tuthill, A.
Power, D. G.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-17
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A 37-year-old male presented with a traumatic injury to the scrotal region necessitating emergency surgery.
Evacuation of a haematoma and bilateral orchidectomy were performed.
A left sided nonseminomatous germ cell tumour (NSGCT), predominantly yolk sac, was identified.
Microscopic margins were positive for tumour.
Initial tumour markers revealed an AFP of 22,854 ng/mL, HCG of <1 mIU/mL, and LDH of 463 IU/L.
Eight weeks after surgery, AFP levels remained elevated at 11,646 ng/mL.
Computed tomography (CT) scanning demonstrated left inguinal adenopathy, 1.5 cm in max dimension.
On review, extensive evidence of scrotal involvement was evident.
His tumour was staged as stage IIIC, poor risk NSGCT.
He was treated with 4 cycles of bleomycin, etoposide, and cisplatin over a 12-week period.
His tumour markers normalised after 3 cycles.
There was a marked improvement noted clinically.
Follow-up CT scans demonstrated complete resolution of his tumour.
He later underwent further surgery to remove a small amount of remaining spermatic cord.
Histology revealed no malignant tissue.
The patient suffered many complications including testosterone deficiency, osteopenia, infertility, and psychological distress.
Discussion.
A small proportion of testicular cancer may present in an atypical manner.
The scrotum and testicle have markedly different embryonic origins and therefore a distinct anatomic separation.
As a result the scrotum is not a typical site of spread of testicular cancer.
Case reports have been described that were managed in a similar manner with good outcomes.
Therefore, even with significant scrotal involvement, if timely and appropriate treatment is administered, complete resolution of the tumour may be achieved.
American Psychological Association (APA)
O’Leary, C. G.& Allen, J. A.& O’Brien, F.& Tuthill, A.& Power, D. G.. 2016. Scrotal Involvement with Testicular Nonseminomatous Germ Cell Tumour. Case Reports in Oncological Medicine،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101699
Modern Language Association (MLA)
O’Leary, C. G.…[et al.]. Scrotal Involvement with Testicular Nonseminomatous Germ Cell Tumour. Case Reports in Oncological Medicine No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1101699
American Medical Association (AMA)
O’Leary, C. G.& Allen, J. A.& O’Brien, F.& Tuthill, A.& Power, D. G.. Scrotal Involvement with Testicular Nonseminomatous Germ Cell Tumour. Case Reports in Oncological Medicine. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101699
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101699