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A Rare Thyroid Metastasis from Uveal Melanoma and Response to Immunotherapy Agents
Joint Authors
Power, D. G.
Collins, Dearbhaile Catherine
Yela, Ruben
Horgan, Noel
Source
Case Reports in Oncological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Thyroid metastasis is a rare occurrence with cutaneous melanoma and even more uncommon with uveal melanoma.
The management of such metastasis is uncertain due to its infrequency and, in the era of immunotherapy, the effect of these novel drugs on uncommon metastasis, such as to the thyroid, is unknown.
We report the rare case of a thyroid metastasis in a patient diagnosed with ocular melanoma initially managed with enucleation.
Metastatic disease developed in the lung and thyroid gland.
The case patient received the immunotherapy ipilimumab with stable disease in the thyroid and progressive disease elsewhere.
The patient was then further treated with a second immunotherapy agent, pembrolizumab, and remains with stable disease one year later.
We discuss the current literature on thyroid metastases from all causes and the optimal known management strategies.
Furthermore, we provide an original report on the response of this disease to the novel immunomodulators, ipilimumab, and pembrolizumab with stable disease four years after initial diagnosis of ocular melanoma.
American Psychological Association (APA)
Collins, Dearbhaile Catherine& Yela, Ruben& Horgan, Noel& Power, D. G.. 2016. A Rare Thyroid Metastasis from Uveal Melanoma and Response to Immunotherapy Agents. Case Reports in Oncological Medicine،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1101704
Modern Language Association (MLA)
Collins, Dearbhaile Catherine…[et al.]. A Rare Thyroid Metastasis from Uveal Melanoma and Response to Immunotherapy Agents. Case Reports in Oncological Medicine No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1101704
American Medical Association (AMA)
Collins, Dearbhaile Catherine& Yela, Ruben& Horgan, Noel& Power, D. G.. A Rare Thyroid Metastasis from Uveal Melanoma and Response to Immunotherapy Agents. Case Reports in Oncological Medicine. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1101704
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101704