Scrotal Apocrine Adenocarcinoma with Pagetoid Phenomenon and Inguinal Lymph Node Metastases
Joint Authors
Zibis, Aristeidis Hristos
Fyllos, Apostolos Haralampos
Havaki, Sophia
Sotiriou, Sotirios
Kotakidis, Georgios
Arvanitis, Demetrios L.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We report a case of scrotal apocrine adenocarcinoma in a 72-year-old Caucasian male which was initially presented as a reddish superficial lesion which in time became an ulcerated nodule.
The initial pathological examination showed an apocrine adenocarcinoma with pagetoid phenomenon.
The tumor recurred after four months and then excision biopsy showed tumor with pagetoid phenomenon which reached all the surgical margins.
Three months later an ulcerated nodule in the scrotum and greatly enlarged ipsilateral inguinal lymph nodes were noticed.
The final pathological examination showed multiple separated malignant foci, some with overlying pagetoid phenomenon and inguinal lymph node metastases.
Immunohistochemistry showed positivity for Gross Cystic Disease Fluid Protein-15 (GCDFP-15), androgen receptors, and score 3+ for the Human Epidermal growth factor Receptor-2 (HER2).
The aggressive behavior of the present tumor goes along with previous reports showing that HER2 high score cases exhibit a worse prognosis.
American Psychological Association (APA)
Zibis, Aristeidis Hristos& Fyllos, Apostolos Haralampos& Havaki, Sophia& Sotiriou, Sotirios& Kotakidis, Georgios& Arvanitis, Demetrios L.. 2016. Scrotal Apocrine Adenocarcinoma with Pagetoid Phenomenon and Inguinal Lymph Node Metastases. Case Reports in Oncological Medicine،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101724
Modern Language Association (MLA)
Zibis, Aristeidis Hristos…[et al.]. Scrotal Apocrine Adenocarcinoma with Pagetoid Phenomenon and Inguinal Lymph Node Metastases. Case Reports in Oncological Medicine No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1101724
American Medical Association (AMA)
Zibis, Aristeidis Hristos& Fyllos, Apostolos Haralampos& Havaki, Sophia& Sotiriou, Sotirios& Kotakidis, Georgios& Arvanitis, Demetrios L.. Scrotal Apocrine Adenocarcinoma with Pagetoid Phenomenon and Inguinal Lymph Node Metastases. Case Reports in Oncological Medicine. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101724
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101724