Chronic Lymphocytic Leukemia with Translocation (2;14)(p16;q32): A Case Report and Review of the Literature
Joint Authors
Socola, Francisco
Insuasti-Beltran, Giovanni
Henrich Lobo, Rodolfo
Atrash, Shebli
Sasapu, Appalanaidu
Source
Case Reports in Oncological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-03
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We report the case of a young African American male with no significant past medical history presenting with low back and bilateral leg pain; presenting CBC and chemistries revealed elevated white blood cell count of 250,000, with anemia (Hb 6.8 g/dL) and thrombocytopenia (platelets 9 K/μL), and elevated LDH, 1008.
Physical examination findings were notable for diffuse lymphadenopathy and lower extremity skin nodules.
Interestingly the bone marrow biopsy revealed involvement by CLL/SLL with translocation (2;14)(p16;q32) and trisomy 12.
The patient was treated with fludarabine-based chemotherapy and steroids for CLL-related ITP with excellent response.
After three cycles of chemotherapy, all the enlarged lymph nodes and skin nodules disappeared, and patient had achieved complete hematologic response.
In this paper we also reviewed the available literature of CLL patients with translocation (2;14).
American Psychological Association (APA)
Socola, Francisco& Insuasti-Beltran, Giovanni& Henrich Lobo, Rodolfo& Atrash, Shebli& Sasapu, Appalanaidu. 2016. Chronic Lymphocytic Leukemia with Translocation (2;14)(p16;q32): A Case Report and Review of the Literature. Case Reports in Oncological Medicine،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101746
Modern Language Association (MLA)
Socola, Francisco…[et al.]. Chronic Lymphocytic Leukemia with Translocation (2;14)(p16;q32): A Case Report and Review of the Literature. Case Reports in Oncological Medicine No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1101746
American Medical Association (AMA)
Socola, Francisco& Insuasti-Beltran, Giovanni& Henrich Lobo, Rodolfo& Atrash, Shebli& Sasapu, Appalanaidu. Chronic Lymphocytic Leukemia with Translocation (2;14)(p16;q32): A Case Report and Review of the Literature. Case Reports in Oncological Medicine. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101746
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101746