Plasmablastic Lymphoma Mimicking Acute Pancreatitis
Joint Authors
Saif, Muhammad Wasif
Inayat, Faisal
Cheema, Ahmad R.
Virk, Hafeez Ul Hasan
Source
Case Reports in Oncological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-13
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Plasmablastic lymphoma (PBL) is a rare B-cell neoplasm.
It predominantly occurs in the oral cavity of human immunodeficiency virus (HIV)-positive patients and exhibits a highly aggressive clinical behavior.
Case Presentation.
We describe an unusual case of a 37-year-old HIV-positive male who presented with acute pancreatitis secondary to multiple peripancreatic masses compressing the pancreas.
Histopathological examination of the lesions showed diffuse and cohesive pattern of large B-cells resembling immunoblasts or plasmablasts.
The neoplastic cells were positive for BOB1 and MUM1, partially positive for CD79a, and negative for CD20, CD56, CD138, CD3, CD5, AE1/AE3, and HHV8.
Epstein-Barr virus-encoded RNA in situ hybridization was positive.
These features were consistent with PBL.
The patient was initiated on cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy, demonstrating a striking response.
Conclusion.
To our research, this is the first report of PBL with the initial presentation of acute pancreatitis.
The findings in this case suggest that PBL should be included in the differential diagnosis of pancreatic and peripancreatic tumors.
American Psychological Association (APA)
Inayat, Faisal& Virk, Hafeez Ul Hasan& Cheema, Ahmad R.& Saif, Muhammad Wasif. 2016. Plasmablastic Lymphoma Mimicking Acute Pancreatitis. Case Reports in Oncological Medicine،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101754
Modern Language Association (MLA)
Inayat, Faisal…[et al.]. Plasmablastic Lymphoma Mimicking Acute Pancreatitis. Case Reports in Oncological Medicine No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1101754
American Medical Association (AMA)
Inayat, Faisal& Virk, Hafeez Ul Hasan& Cheema, Ahmad R.& Saif, Muhammad Wasif. Plasmablastic Lymphoma Mimicking Acute Pancreatitis. Case Reports in Oncological Medicine. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101754
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101754