Necrotizing Retinitis Secondary to Congenital Cytomegalovirus Infection Associated with Severe Combined Immunodeficiency
Joint Authors
Ozcan, Pehmen Yasin
Celik, Hasan Tolga
Sonmez, Kenan
Celik, Melda
Source
Case Reports in Ophthalmological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-23
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A 20-day-old male infant who was born at 39 weeks of gestation was admitted to neonatal intensive care unit due to severe respiratory insufficiency.
In retinal examination, peripheric retinal white-black color areas that correspond to necrotizing retinitis, moderate vitritis, macular and optic nerve head involvement, vascular leakage, and sheathing indicating perivasculitis were revealed.
Despite the fact that CMV specific IgM was undetectable, CMV DNA with high viral load was found in his blood sample by means of real-time polymerase chain reaction assay.
Serologic examination (IgM) for rubella, toxoplasma, herpes simplex type 2, and human immunodeficiency virus (anti-HIV) was negative.
During the further evaluation for systemic immune dysfunction, decreased immunoglobulin and lymphocyte levels that confirm the diagnosis of severe combined immunodeficiency have been reached.
Although given systemic intravenous ganciclovir and antibiotics treatment, the patient died at the 4th month of life due to respiratory insufficiency.
American Psychological Association (APA)
Ozcan, Pehmen Yasin& Celik, Hasan Tolga& Sonmez, Kenan& Celik, Melda. 2016. Necrotizing Retinitis Secondary to Congenital Cytomegalovirus Infection Associated with Severe Combined Immunodeficiency. Case Reports in Ophthalmological Medicine،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101778
Modern Language Association (MLA)
Ozcan, Pehmen Yasin…[et al.]. Necrotizing Retinitis Secondary to Congenital Cytomegalovirus Infection Associated with Severe Combined Immunodeficiency. Case Reports in Ophthalmological Medicine No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1101778
American Medical Association (AMA)
Ozcan, Pehmen Yasin& Celik, Hasan Tolga& Sonmez, Kenan& Celik, Melda. Necrotizing Retinitis Secondary to Congenital Cytomegalovirus Infection Associated with Severe Combined Immunodeficiency. Case Reports in Ophthalmological Medicine. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101778
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101778