Bilateral Lacrimal Gland Lymphoma in Sjögren Syndrome
Joint Authors
Sahin, Fahri
Ozsan, Nazan
Palamar, Melis
Source
Case Reports in Ophthalmological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-21
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A 31-year-old female with Primary Sjögren Syndrome (pSS) presented with bilateral puffiness around the eye for 3 years.
The lacrimal glands were hypertrophic and edematous bilaterally.
Schirmer 1 score was 2 and 1 mm and tear-film break-up time was 3 and 4 seconds, in the right and the left eyes, respectively.
An incisional biopsy from the left lacrimal gland revealed diffuse and intense CD20, CD5, and bcl-2 positivity with negative cyclin D1 and CD23 which supported lymphoma.
Upon haematology consultation extranodal marginal zone lymphoma diagnosis was made.
CHOP (cyclophosphamide, doxorubicin, vincristine, and methyl prednisolone) treatment was initiated.
In conclusion, pSS is a well known autoimmune disease in which increased rate of lymphoma is present.
Early detection with histopathologic confirmation and multidisciplinary approach with ophthalmology, rheumatology, and haematology are mandatory in these patients.
American Psychological Association (APA)
Palamar, Melis& Ozsan, Nazan& Sahin, Fahri. 2016. Bilateral Lacrimal Gland Lymphoma in Sjögren Syndrome. Case Reports in Ophthalmological Medicine،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101790
Modern Language Association (MLA)
Palamar, Melis…[et al.]. Bilateral Lacrimal Gland Lymphoma in Sjögren Syndrome. Case Reports in Ophthalmological Medicine No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1101790
American Medical Association (AMA)
Palamar, Melis& Ozsan, Nazan& Sahin, Fahri. Bilateral Lacrimal Gland Lymphoma in Sjögren Syndrome. Case Reports in Ophthalmological Medicine. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1101790
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101790