Pseudotumor Cerebri in a Child with Idiopathic Growth Hormone Insufficiency Two Months after Initiation of Recombinant Human Growth Hormone Treatment
Joint Authors
Loukianou, Eleni
Tasiopoulou, Anastasia
Demosthenous, Constantinos
Brouzas, Dimitrios
Source
Case Reports in Ophthalmological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To report a rare case of pseudotumor cerebri (PTC) in a child two months after receiving treatment with recombinant human growth hormone (rhGH) and to emphasize the need of close collaboration between ophthalmologists and pediatric endocrinologists in monitoring children receiving rhGH.
Methods.
A 12-year-old boy with congenital hypothyroidism started treatment with rhGH on a dose of 1,5 mg/daily IM (4.5 IU daily).
Eight weeks later, he was complaining of severe headache without any other accompanying symptoms.
The child was further investigated with computed tomography scan and lumbar puncture.
Results.
Computed tomography scan showed normal ventricular size and lumbar puncture revealed an elevated opening pressure of 360 mm H2O.
RhGH was discontinued and acetazolamide 250 mg per os twice daily was initiated.
Eight weeks later, the papilledema was resolved.
Conclusions.
There appears to be a causal relationship between the initiation of treatment with rhGH and the development of PTC.
All children receiving rhGH should have a complete ophthalmological examination if they report headache or visual disturbances shortly after the treatment.
Discontinuation of rhGH and initiation of treatment with acetazolamide may be needed and regular follow-up examinations by an ophthalmologist should be recommended.
American Psychological Association (APA)
Loukianou, Eleni& Tasiopoulou, Anastasia& Demosthenous, Constantinos& Brouzas, Dimitrios. 2016. Pseudotumor Cerebri in a Child with Idiopathic Growth Hormone Insufficiency Two Months after Initiation of Recombinant Human Growth Hormone Treatment. Case Reports in Ophthalmological Medicine،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1101818
Modern Language Association (MLA)
Loukianou, Eleni…[et al.]. Pseudotumor Cerebri in a Child with Idiopathic Growth Hormone Insufficiency Two Months after Initiation of Recombinant Human Growth Hormone Treatment. Case Reports in Ophthalmological Medicine No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1101818
American Medical Association (AMA)
Loukianou, Eleni& Tasiopoulou, Anastasia& Demosthenous, Constantinos& Brouzas, Dimitrios. Pseudotumor Cerebri in a Child with Idiopathic Growth Hormone Insufficiency Two Months after Initiation of Recombinant Human Growth Hormone Treatment. Case Reports in Ophthalmological Medicine. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1101818
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101818