A Gel Formulation Containing a New Recombinant Form of Manganese Superoxide Dismutase: A Clinical Experience Based on Compassionate Use-Safety of a Case Report
Joint Authors
Mancini, Aldo
Grumetto, Lucia
Ortosecco, Giovanni
Del Prete, Salvatore
Borrelli, Antonella
Prete, Antonio Del
Source
Case Reports in Ophthalmological Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-17
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
We report a case of bilateral posterior subcapsular cataracts (PSCs) in a 24-year-old man with an allergic conjunctivitis history caused by a long-term therapy with glucocorticoids.
Case Presentation.
The patient showed a visual acuity of 9/10 for both eyes.
He followed a therapy with ketotifen and bilastine for four years.
During the last six months before our evaluation, he was treated with chloramphenicol and betamethasone, interrupted for onset of cataracts and increased intraocular pressure.
We treated him with ophthalmic gel preparation containing a new recombinant form of manganese superoxide dismutase (rMnSOD) at a concentration of 12.5 μg/mL, only for the right eye, while left eye was treated with standard protocol of Bendazac-lysine g 0.5.
Conclusion.
This case report shows the protective effects of rMnSOD versus PSC disease, probably due to the capacity of rMnSOD of countering free radical species.
American Psychological Association (APA)
Grumetto, Lucia& Prete, Antonio Del& Ortosecco, Giovanni& Borrelli, Antonella& Del Prete, Salvatore& Mancini, Aldo. 2016. A Gel Formulation Containing a New Recombinant Form of Manganese Superoxide Dismutase: A Clinical Experience Based on Compassionate Use-Safety of a Case Report. Case Reports in Ophthalmological Medicine،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101848
Modern Language Association (MLA)
Grumetto, Lucia…[et al.]. A Gel Formulation Containing a New Recombinant Form of Manganese Superoxide Dismutase: A Clinical Experience Based on Compassionate Use-Safety of a Case Report. Case Reports in Ophthalmological Medicine No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1101848
American Medical Association (AMA)
Grumetto, Lucia& Prete, Antonio Del& Ortosecco, Giovanni& Borrelli, Antonella& Del Prete, Salvatore& Mancini, Aldo. A Gel Formulation Containing a New Recombinant Form of Manganese Superoxide Dismutase: A Clinical Experience Based on Compassionate Use-Safety of a Case Report. Case Reports in Ophthalmological Medicine. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101848
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101848