![](/images/graphics-bg.png)
A Woman with Rheumatoid Arthritis and a Bilateral Fracture of the Proximal Tibia
Joint Authors
Hooghof, J. Th. (Arjan)
Mellema, Joris J.
Posthumus, Marcel D.
van Raaij, Jos J. A. M.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-11
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
A 52-year-old woman presented herself with pain on the medial sides of the proximal tibia after a minimal trauma.
Conventional X-rays did not show any pathology.
However, the MRI showed a bilateral fracture of the proximal tibia.
Since the patient was treated with methotrexate due to rheumatoid arthritis, methotrexate osteopathy was considered.
Long term treatment with low doses of methotrexate proved to inhibit osteoblast proliferation and may eventually lead to decreased bone formation and osteopenia.
On the other hand, immobilization, joint deformities, and steroid treatment are associated with rheumatoid arthritis and are also known risk factors for fractures.
The clinical relevance of methotrexate osteopathy still has to be established.
However, if a patient treated with methotrexate localizes pain in the tibia, methotrexate osteopathy should be considered.
Withdrawal of the drug may improve symptoms.
American Psychological Association (APA)
Hooghof, J. Th. (Arjan)& Mellema, Joris J.& Posthumus, Marcel D.& van Raaij, Jos J. A. M.. 2016. A Woman with Rheumatoid Arthritis and a Bilateral Fracture of the Proximal Tibia. Case Reports in Orthopedics،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101997
Modern Language Association (MLA)
Hooghof, J. Th. (Arjan)…[et al.]. A Woman with Rheumatoid Arthritis and a Bilateral Fracture of the Proximal Tibia. Case Reports in Orthopedics No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1101997
American Medical Association (AMA)
Hooghof, J. Th. (Arjan)& Mellema, Joris J.& Posthumus, Marcel D.& van Raaij, Jos J. A. M.. A Woman with Rheumatoid Arthritis and a Bilateral Fracture of the Proximal Tibia. Case Reports in Orthopedics. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1101997
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1101997